Serum Sickness and Serum Sickness-Like Reaction

Reshamwala, Neha; Mahmoudi, Massoud

doi:10.1007/978-1-60761-296-4_7

Cited by 1 publication

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cutaneous manifestations include fixed, polycyclic urticarial lesions, and other nonspecific pruritic rashes that may appear maculopapular. There are also associated extracutaneous symptoms including fever, malaise, polyarthralgia, and angioedema (Wener, 2022). Classic serum sickness is rare in children because medications or animal serum that contain a foreign protein antigen are rarely administered to this age group (Shah et al, 2007).…”

Section: Serum Sickness Reactionsmentioning

confidence: 99%

“…Serum sickness-like reactions (SSLRs) occur more frequently and may not be dependent on high titers of antibodies and circulating immune complexes, as in classic serum sickness, although the pathogenesis is not completely understood (Wener, 2022). As compared with classic serum sickness, SSLRs occur most commonly in children.…”

Section: Serum Sickness Reactionsmentioning

confidence: 99%

“…As compared with classic serum sickness, SSLRs occur most commonly in children. SSLRs most commonly occur following the use of antibiotics (e.g., cefaclor, amoxicillin, and sulfamethoxazole-trimethoprim), viral infections (e.g., hepatitis B), bacterial infections (e.g., streptococcal), and some vaccines (e.g., pneumococcal, rabies) (Shah et al, 2007;Wener, 2022).…”

Section: Serum Sickness Reactionsmentioning

confidence: 99%

“…The urticarial skin lesions typically gradually expand, leaving central clearing or central faint purpura, which are usually most evident on the abdomen or lower legs. Extracutaneous symptoms typically include low-grade fever, arthralgias, and angioedema (Wener, 2022). The mucous membranes are usually spared.…”

Section: Serum Sickness Reactionsmentioning

confidence: 99%

“…The mucous membranes are usually spared. Symptoms typically develop with 1-2 weeks of exposure to the antigenic agent and may last for up to 2 weeks (Wener, 2022).…”

Section: Serum Sickness Reactionsmentioning

confidence: 99%

See 4 more Smart Citations

Urticaria Multiforme

Jordan

Carpenter

2022

Advanced Emergency Nursing Journal

View full text Add to dashboard Cite

The differential diagnosis of rashes in children is challenging. Pediatric rashes indicate a broad spectrum of clinical conditions and include those that are benign and self-limiting to those that may indicate a serious multisystem inflammatory response. It is essential that emergency nurse practitioners have the knowledge and skill set to accurately identify the spectrum of rashes in the pediatric population to arrive at the correct diagnosis for patient management and avoid costly and unnecessary diagnostic testing. The purpose of this article is to describe a case report of a young child with urticaria multiforme, a commonly misdiagnosed clinical condition, including the distinctive clinical features, differential diagnosis, and most current treatment recommendations. Other clinical conditions that present with skin lesions resembling urticaria multiforme conditions have also been discussed.

show abstract

Section: Serum Sickness Reactionsmentioning

confidence: 99%

Section: Serum Sickness Reactionsmentioning

confidence: 99%

Section: Serum Sickness Reactionsmentioning

confidence: 99%

Section: Serum Sickness Reactionsmentioning

confidence: 99%

“…The mucous membranes are usually spared. Symptoms typically develop with 1-2 weeks of exposure to the antigenic agent and may last for up to 2 weeks (Wener, 2022).…”

Section: Serum Sickness Reactionsmentioning

confidence: 99%

See 3 more Smart Citations