Serum selenium in adult Czechoslovak (central bohemia) population

Korunová, Vlasta; Škodová, Z; Dedina, Jiri; Valenta, Zdeněk; Parízek, J; Písa, Z; Stýblo, Miroslav

doi:10.1007/bf02783784

Cited by 36 publications

(14 citation statements)

References 43 publications

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“…Late-pregnant cows were found to suffer from selenium deficiency more frequently than lactating cows . Our finding of a generally high occurrence of selenium deficiency in cattle in the Czech Republic is consistent with the data on the selenium status of the human population which indicate that the Czech Republic ranks with countries with a very low selenium intake and blood selenium concentrations below the European mean (Korunová et al 1993;Kvíãala et al 1994;Kvíãala et al 1995a;Kvíãala et al 1995b;Kuãera et al 1995;Kvíãala et al 1999). …”

Section: Resultssupporting

confidence: 89%

Selenium Status of Cattle in the Czech Republic

Pavlata¹,

Illek²,

Pechová³

et al. 2002

Acta Vet. Brno

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Selenium status was assessed directly by determination of selenium concentration, or indirectly by measurement of glutathione peroxidase activity in whole blood samples collected from 879 cattle (733 cows, 63 calves, 42 heifers, 41 finishing bulls) reared on 93 farms in 12 of the 14 regions of the Czech Republic. Selenium deficiency or marginal values were found in 50 % of the tested animals and on 54 % of the farms. In terms of animal categories, deficient or marginal selenium status was found in 42 % of cows, 80 % of calves, 100 % of heifers, and 90 % of bulls. Seleniumdeficient herds were detected in almost all regions of the Czech Republic. The lowest selenium concentrations (< 20 µg . l -1 whole blood) were found in western, northern, and north-eastern Bohemia and in northern Moravia. It is evident that selenium deficiency in cattle is a topical problem in the Czech Republic and that selenium status must be monitored within preventive diagnostics in all age groups of cattle to decide correctly on the most effective way of supplementation.

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Section: Resultssupporting

confidence: 89%

Selenium Status of Cattle in the Czech Republic

Pavlata¹,

Illek²,

Pechová³

et al. 2002

Acta Vet. Brno

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“…The serum selenium concentration in men and women in our study is very similar, which agrees with most of the authors [13,29,30] . But some others have found these concentrations to be higher in men than in women [31,32] , which was explained as a consequence of different food habits corresponding to differences in body mass [32] .…”

Section: Discussionsupporting

confidence: 82%

Food Intake and Serum Selenium Concentration in Elderly People

et al. 2006

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Background/Aims: It is becoming apparent that the essential trace element selenium plays a critical role in the maintenance of optimal health status. The objective of this study was to identify the food groups that most contributed to selenium intake and its serum levels in elderly people. Methods: Dietary intake was assessed in 205 institutionalized elderly by means of a 1-year food frequency questionnaire (FFQ). Intake of macronutrients and minerals of the diet were estimated. Selenium was determined in serum and analyzed by graphite-furnace atomic absorption spectrometry. Results: Selenium intake and serum concentration were both within the normal range. The major contributors to selenium intake were cereals and bakery, fish and shellfish, meat and meat products and dairy products. All of them except cereals were also associated to serum selenium. Intake of animal protein, but not the vegetable one, contributed to serum selenium. Conclusion: An adequate intake of fish and meat would be of importance to improve selenium status and health principally in elderly people who are at high risk of mineral deficiency.

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“…Selenium content in the ALI medium was determined as described before [22] by flow injection hydride generation-/in-situ/ trapping in graphite furnace-atomic absorption spectrometry. An Analyst 800 spectrometer (Perkin-Elmer, Norwalk, Mass, U.S.A.) equipped with FIAS 400 flow injection accessory was employed.…”

Section: Analysis Of Selenium Levelsmentioning

confidence: 99%

Selenium deficiency alters epithelial cell morphology and responses to influenza

Jaspers

Zhang

Brighton

et al. 2007

Free Radical Biology and Medicine

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It is unknown whether nutritional deficiencies affect the morphology and function of structural cells, such as epithelial cells, and modify the susceptibility to viral infections. We developed an in vitro system of differentiated human bronchial epithelial cells (BEC) grown either under selenium adequate (Se+) or selenium deficient (Se-) conditions, to determine whether selenium deficiency impairs host defense responses at the level of the epithelium. Se-BECs had normal SOD activity, but decreased activity of the selenium-dependent enzyme GPX1. Interestingly, catalase activity was also decreased in Se-BECs. Both Se-and Se+ BECs differentiated into a mucociliary epithelium; however, Se-BEC demonstrated increased mucus production and increased Muc5AC mRNA levels. This effect was also seen in Se+ BEC treated with 3-aminotriazole, and inhibitor of catalase activity, suggesting an association between catalase activity and mucus production. Both Se-and Se+ were infected with influenza A/Bangkok/1/79 and examined 24 hours post-infection. Influenza-induced IL-6 production was greater while influenza-induced IP-10 production was lower in Se-BECs. In addition, influenza-induced apoptosis was greater in Se-BEC as compared to the Se+ BECs. These data demonstrate that selenium deficiency has a significant impact on the morphology and influenzainduced host defense responses in human airway epithelial cells.

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Serum selenium in adult Czechoslovak (central bohemia) population

Cited by 36 publications

References 43 publications

Selenium Status of Cattle in the Czech Republic

Selenium Status of Cattle in the Czech Republic

Food Intake and Serum Selenium Concentration in Elderly People

Selenium deficiency alters epithelial cell morphology and responses to influenza

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