Serum proteomic biomarker investigation of vascular depression using data-independent acquisition: a pilot study
Liuyi Lan,
Sisi Peng,
Ran Zhang
et al.
Abstract:BackgroundVascular depression (VaD) is a depressive disorder closely associated with cerebrovascular disease and vascular risk factors. It remains underestimated owing to challenging diagnostics and limited information regarding the pathophysiological mechanisms of VaD. The purpose of this study was to analyze the proteomic signatures and identify the potential biomarkers with diagnostic significance in VaD.MethodsDeep profiling of the serum proteome of 35 patients with VaD and 36 controls was performed using … Show more
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