“…They have revealed that exercise had changed the morphology of the third metacarpal bones [3,12,13,19,25]. Chiba et al [7] and Yoshikawa et al [24] have pointed out that the endocrine system was related to fracture in horses. Nevertheless, it was difficult to find other researches into bone disease which had been related to the endocrine systems, such as the thyroid and parathyroid.…”