Serum Mg, Zn and Fe levels among coronary artery disease patients in an urban south Indian region

Abstract

Nutrition plays a crucial role in CAD development, with trace elements like zinc, magnesium, copper, and iron impacting atherogenesis through their antioxidant or oxidant activity. This cross sectional study was conducted under the ICMR-STS program with IEC approval with the aim to estimate and correlate serum magnesium, zinc, and iron levels in CAD patients compared to healthy Individuals in the Urban South Indian population (50 cases, 50 controls, aged 40-70 years). Statistical analyses revealed a significant difference in serum iron levels between cases (95.10 ą 38.82 μg/dL) and controls (118.30 ą 50.54 μg/dL) with a p-value of 0.012. Serum magnesium levels showed a marginal difference between cases (1.97ą0.11 mg/dL) and controls (1.92ą0.15 mg/dL) with a p-value of 0.053. However, serum zinc levels did not exhibit a statistically significant difference between cases (123.47 ą 26.35 mg/dL) and controls (118.90 ą 32.77 mg/dL) with a p-value of 0.445. Thus, data shows the association between low serum iron levels and an increased risk of coronary artery disease.