Serum levels of β-carotene and other carotenoids in Parkinson's disease

Vitamin A and Carotenoids and the Risk of Parkinson's Disease: A Systematic Review and Meta-Analysis

“…None of the four studies measuring vitamin A in serum reported a measure of association with PD. They all reported mean or median differences only and, although in three studies differences favour cases compared to controls, differences are so small that these could be assumed to be negligible [30,33,36]; in another cross-sectional study the same median in cases and controls was reported [29]. …”

“…A total of 21 papers passed the title and abstract screening and were assessed for eligibility [17,18,19,20,21,22,24,26,27,28,29,30,31,32,33,34,35,36,37,38,39]. Of these, two were excluded because the exposure measurement was not available [26,27], four because they did not provide original data [28,32,38] and three because the full text was not available [31,34,37].…”

“…Vitamin A or retinoic acid was assessed in eight studies [17,18,24,29,30,33,36,39], of which only one was a case-control nested in a cohort study [17]. Estimates of the association between dietary vitamin A intake and risk of PD were not consistent: two good-quality, powered population-based case-control studies estimated a non-significant OR comparing the 4th versus the 1st quartile of distribution in the opposite direction [18,24] (fig.…”

Epidemiology and etiology of Parkinson’s disease: a review of the evidence

“…Results have been conflicting. One study reported lower serum levels of vitamins E and A in PD cases than in controls [495], but most early casecontrol studies that examined serum levels of vitamin C, vitamin E, beta-carotene, or vitamin A found no associations [496][497][498][499][500]. A German hospital-based case-control study [486] reported an inverse relationship between vitamin C intake and PD (p for trend 0.04; OR for highest quartile compared to lowest 0.60, 95% CI 0.33-1.09), but no association with vitamin E or beta-carotene intake.…”

Gènes et absorption intestinale des microconstituants lipidiques (vitamines liposolubles, caroténoïdes et phytostérols)

“…Sont qualifi es de microconstituants lipidiques ceux qui ne sont pas solubles dans l'eau mais qui le sont dans des solvants organiques. [4][5][6][7]. Par ailleurs, la lut eine et la z eaxanthine, deux carot enoïdes appartenant a la sous-classe des xanthophylles, semblent jouer un rôle important dans la fonction oculaire et pourraient pr evenir la cataracte et la d eg en erescence maculaire li ee a l'âge [6,8,9].…”