Serum Levels of Mid-Regional Pro-adrenomedullin and Soluble Triggering Receptor Expressed on Myeloid Cells in Cattle with Pneumonia

Abstract

This study was aimed at the determination of the serum levels of two inflammatory biomarkers, namely, mid-regional pro-adrenomedullin and soluble triggering receptor expressed on myeloid cells, as well as some biochemical and hematological parameters in cattle diagnosed with pneumonia. For this purpose, 40 patient female cattle, which were aged 2-7 years and displayed coughing, dyspnea, nasal discharge, anorexia and abdominal respiration, and 15 healthy female cattle within the same age range, were evaluated. The diseased cattle underwent clinical and radiological examinations and were sampled for blood prior to receiving treatment. The healthy subjects also underwent clinical examination and were sampled for blood once. The blood samples were used for biochemical and hematological measurements. The healthy and diseased cattle showed statistically significant differences for the serum levels of mid-regional pro-adrenomedullin and soluble triggering receptor expressed on myeloid cells (P