Serum leptin and cholesterol values in violent and non-violent suicide attempters

Serum triglycerides, but not cholesterol or leptin, are decreased in suicide attempters with mood disorders

“…(Atmaca et al, 2008)]. We did not find a significant difference in serum cholesterol between violent and non-violent attempters, in agreement with a previous study in BD (D'Ambrosio et al, 2012).…”

“…(McConway et al, 2000)]. Leptin (together with cholesterol) was found to be reduced in suicidal patients, compared to healthy controls (Atmaca et al, 2008(Atmaca et al, , 2002. In addition, low levels of cerebrospinal leptin were found in female suicide attempters with major depression (Westling et al, 2004), in agreement with reduced levels of brain leptin observed in suicide victims (Eikelis et al, 2006).…”

“…We aimed to determine whether total cholesterol, its fractions and triglycerides were decreased in subjects that had attempted suicide, as well as to investigate serum levels of other proteins putatively associated with suicidal behavior: leptin (Atmaca et al, 2008), S100B protein (Falcone et al, 2010), brainderived neurotrophic factor (BDNF) (Pandey et al, 2010) and C-reactive protein (CRP) (De Berardis et al, 2008).…”

Serum lipid levels and suicidality: a meta-analysis of 65 epidemiological studies

“…In addition, when compared with healthy controls, patients with violent suicide attempts had much larger mean serum TC level differences than those with nonviolent suicide attempts. This result indicates that patients with violent suicide attempts had lower TC levels than those with nonviolent suicide attempts, as the individual studies 34,38,41,46 revealed. However, 1 study found there was no difference between patients with violent and nonviolent suicide attempts.…”

Associations between serum lipid levels and suicidal ideation among Korean older people

“…Several studies have reported that cholesterol levels might be linked more to the violence of a suicide attempt rather than to suicidality itself (Alvarez et al, 2000;Atmaca et al, 2008;Vevera et al, 2003). Others have suggested that lower cholesterol levels might be associated with the lipid microviscosity of serotonin receptors and transporters and reduced serotonin activity, resulting in impulsive and suicidal behavior (Engelberg, 1992;Mann, 2003).…”