Serum immunoglobulin G concentration in Southern elephant seal, Mirounga leonina (Linnaeus, 1758), from Elephant island (Antarctica): Sexual and adrenal steroid hormones effects

Ferreira, Ana Paula Sacone da Silva; Martinez, Pablo Elías; Colares, Elton Pinto; Robaldo, Ricardo Berteaux; Berne, M. E. A.; Filho, Kleber C. Miranda; Bianchini, Adalto

doi:10.1016/j.vetimm.2005.02.024

Cited by 12 publications

(9 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Age significantly influenced hair cortisol concentration in Egyptian mongoose, with early stage juveniles, between two-and-a-half and five-and-a-half months, exhibiting higher levels of hair cortisol than other age cohorts (Fig 2a). This age cohort includes the recently weaned mongoose pups [56] and is consistent with the post-weaning cortisol increase found in the southern elephant seal [33]. Elevated glucocorticoid secretion during infancy has been described using faecal glucocorticoid metabolite analysis in baboons [57] and hair cortisol in non-human primates [58] and humans [59].…”

Section: Discussionsupporting

confidence: 55%

“…Each individual’s baseline adrenocortical activity and HPA-axis reactivity is influenced by genetic inheritance [23,24], maternal and epigenetic effects [25–27], biotic environmental factors like infection or predation risk [28,29] and abiotic factors like weather and climate [30,31]. Additionally, glucocorticoid levels may vary with sex [32], developmental stage [33,34] and age [11,35]. Although often not evident in studies using captive animals, seasonal variations in glucocorticoids levels have been demonstrated in wild species [36,37].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Age, sex and storage time influence hair cortisol levels in a wild mammal population

Azevedo¹,

Bailey²,

Bandeira³

et al. 2019

PLoS ONE

View full text Add to dashboard Cite

The measurement of hair cortisol is increasingly used to understand the effect of natural and anthropogenic stressors on wild animals, but it is potentially confounded by individual, seasonal and sex-dependant variations in baseline cortisol secretion. This study validated an enzyme-linked immunoassay for hair cortisol measurement and characterized its baseline variation in a wild population of Egyptian mongoose. The analysis encompassed individuals of both sexes and all ages, across a range of geographic, environmental and seasonal conditions that the species experiences in Portugal allowing us to account for spatial, temporal and biological factors that contribute to hair cortisol variation. Our results showed that age, sex and storage time had an effect on hair cortisol, but season did not. Hair cortisol was higher in early stage juveniles compared to other age cohorts, in males when compared to females, and decreased with longer storage time. By identifying the factors that influence baseline hair cortisol in this wild population, we establish the basis for its application as an indicator of the effect of natural and anthropogenic stressors.

show abstract

Section: Discussionsupporting

confidence: 55%

Section: Introductionmentioning

confidence: 99%

Age, sex and storage time influence hair cortisol levels in a wild mammal population

Azevedo¹,

Bailey²,

Bandeira³

et al. 2019

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Aubin and Geraci 1986;Ferreira et al 2005) and Ang II (Zenteno-Savin and Castellini 1998) concentrations in adult or juvenile pinnipeds are scarce. Mean aldosterone concentrations during the early period ( pg/mL) were most similar to those measured 145 ‫ע‬ 11 ( pg/mL) in wild adult (values for males and females 139 ‫ע‬ 75 combined as reported) southern elephant seals (Mirounga leonina) during their molting fast (Ferreira et al 2005) and were approximately half those reported for captive juvenile ringed seals (Phoca hispida) during normonatremic, salt-replete conditions (St. Aubin and Geraci 1986). Samples obtained from wild adult male gray seals (Halichoerus grypus) ranged from 1,390 to 3,300 pg/mL; however, it should be noted that these samples were obtained from animals that were shot to death, which may explain the comparatively high concentrations (Sangalang and Freeman 1976).…”

Section: Discussionmentioning

confidence: 99%

Angiotensin II and Aldosterone Increase with Fasting in Breeding Adult Male Northern Elephant Seals (Mirounga angustirostris)

Ortiz¹,

Crocker²,

Houser³

et al. 2006

Physiological and Biochemical Zoology

View full text Add to dashboard Cite

JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact support@jstor.org.. The University of Chicago Press ABSTRACTThe renin-angiotensin-aldosterone system (RAAS) appears to contribute significantly to osmoregulation of fasting northern elephant seal (Mirounga angustirostris) pups; however, RAAS has not been characterized in fasting adult seals. Therefore, this study examined the contribution of RAAS to water turnover rates in fasting adult male northern elephant seals. Blood samples were obtained twice during their breeding fast at an interval of 6.5 wk, and water efflux rate was estimated by isotopic dilution during the same period. Serum electrolytes (Na ϩ , K ϩ , Cl Ϫ ) and osmolality were unaltered between the two sampling periods, indicating ionic and osmotic homeostasis during the fast. Despite the lack of an increase in vasopressin, serum angiotensin II and aldosterone were increased and were significantly and positively correlated. Changes in aldosterone concentration and water efflux rate were significantly and negatively correlated, suggesting that the greater the increase in aldosterone, the smaller the loss of water. Adult male seals maintain ionic and osmotic homeostasis similar to that of fasting weaned pups, and this homeostasis appears to be mediated, at least in part, by RAAS, which probably contributes to increased water retention as well. The hormonal mechanisms by which northern elephant seals maintain water and electrolyte balance during fasting conditions appear to be similar regardless of age.

show abstract

“…Neonates of most mammal groups, exemplified by humans, cattle, pigs, camels, dogs, and cats, exhibit concentrations of maternal immunoglobulins in their blood equivalent to or even greater than their mothers by birth, or within a matter of hours thereafter, despite acquiring maternal immunoglobulins by different mechanisms (Brambell, 1970;Simister, 2003;Roopenian and Akilesh, 2007;Langer, 2008;Wooding and Burton, 2008;Langer, 2009;Westrom et al, 2020). The true, phocid, seals are exceptions to this, in that neonates exhibit levels of immunoglobulin that are a fraction of adult levels, even after taking colostrum (Ross et al, 1994;King et al, 1998;Hall et al, 2003;Ferreira et al, 2005). The concentrations of immunoglobulins then build slowly after birth, but barely reach adult levels by the time they are weaned (Ross et al, 1994;King et al, 1998;Hall et al, 2003;Ferreira et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

“…The true, phocid, seals are exceptions to this, in that neonates exhibit levels of immunoglobulin that are a fraction of adult levels, even after taking colostrum (Ross et al, 1994;King et al, 1998;Hall et al, 2003;Ferreira et al, 2005). The concentrations of immunoglobulins then build slowly after birth, but barely reach adult levels by the time they are weaned (Ross et al, 1994;King et al, 1998;Hall et al, 2003;Ferreira et al, 2005). The source of these immunoglobulins (principally IgG) is not understood but suspected to be mainly or entirely produced by the neonate alone, and not gifted by the mother, although there is some evidence of trans-colostral transfer (Ross et al, 1994;King et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Is a Little Enough? Paucity of Immune Proteins in Serum of Precocial Neonates of a Marine Carnivoran—the Atlantic Grey Seal

et al. 2022

View full text Add to dashboard Cite

Mammalian mothers usually provide their offspring with large quantities of immunoglobulins (antibodies) for circulation in blood, either trans-placentally before birth, via colostrum briefly thereafter, or, less commonly, from milk. Neonates of true, phocid seals, however, are peculiarly impoverished in serum immunoglobulins, the levels of which slowly increase but do not reach adult levels by the time of weaning. We investigated whether grey seal (Halichoerus grypus) neonates compensate through an elevation or rapid maturation in levels of serum innate immune factors, namely acute phase and complement proteins. Instead, their sera contained remarkably low levels of acute phase proteins (including C-reactive protein, haptoglobin, hemopexin, ceruloplasmin, orosomucoid), compared to their mothers, that barely increased to adult levels by weaning. For complement, there was a strong demarcation between the early activation and amplification cascade components (present at normal adult levels in pups) and the late lytic membrane attack complex and regulatory proteins (consistently at low relative levels). Phocid neonates therefore differ dramatically from land Carnivorans, such as dogs and cats, in early life immune protection. That neonatal phocids survive this apparent vulnerability to infections between birth and weaning prompts questions as to what other mechanisms protect them, and the adaptive value of their seeming vulnerability.

show abstract

Serum immunoglobulin G concentration in Southern elephant seal, Mirounga leonina (Linnaeus, 1758), from Elephant island (Antarctica): Sexual and adrenal steroid hormones effects

Cited by 12 publications

References 21 publications

Age, sex and storage time influence hair cortisol levels in a wild mammal population

Age, sex and storage time influence hair cortisol levels in a wild mammal population

Angiotensin II and Aldosterone Increase with Fasting in Breeding Adult Male Northern Elephant Seals (Mirounga angustirostris)

Is a Little Enough? Paucity of Immune Proteins in Serum of Precocial Neonates of a Marine Carnivoran—the Atlantic Grey Seal

Contact Info

Product

Resources

About