Serum IgG subclasses levels in paediatric patients with pneumonia

Abstract

Subjects: 56 paediatric patients. Main Outcome Measures: IgG subclass profiles of children with pneumonia. Results: Of the 56 children tested, 40 (71%) had antibodies to human immunodeficiency virus (HIV). The levels of IgGl and IgG3 subclasses were significantly higher in HIV antibody positive children (p<0.001, p<0.01 respectively) than in those without detectable HIV antibodies in their sera. There was no significant relationship between IgG subclass levels and the presence of HIV p24 antigen. Furthermore, age and gender also had no significant influence on the levels of IgG subclasses in this population.

Effect of 25 weeks probiotic supplementation on immune function of HIV patients

“…30 Elevated levels of IgG among HIV patients have been previously reported, although these may have been due to sub-clinical opportunistic infections. 32 This is one of few studies to examine the safety of long-term use of probiotics, and the first to do so in a population with HIV. 33 No adverse events were associated with the long term use of probiotics.…”

Cryptococcus neoformans -Reactive and Total Immunoglobulin Profiles of Human Immunodeficiency Virus-Infected and Uninfected Ugandans

“…However, those with a history of pneumonia did not have higher levels of antibodies to pneumococcal polysaccharides, and levels of antibodies to GXM and pneumococcal polysaccharides were not correlated. HIV-infected African children with acute pneumonia and adults with pneumococcal pneumonia had high levels of IgM and IgG (32,46). Although pneumococcus was the causative agent in 46% of Kenyans with pneumonia with an identified etiology (58) and 30% of Ugandans (66), the etiology of most cases of pneumonia in Africans is unknown.…”