Serum IgE concentrations in complete Behçet's disease.

Cengiz, K.

doi:10.1136/jcp.43.3.262-a

Cited by 5 publications

(3 citation statements)

References 7 publications

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“…Previous studies have shown that the IGL locus or genes polymorphisms are associated with autoimmune disorders 38 39. In addition, an association between BD and elevations of some immunoglobulins has been noted 40–43…”

Section: Discussionmentioning

confidence: 99%

Genetics of Behcet disease inside and outside the MHC

Meguro

Inoko

Ôta

et al. 2009

Annals of the Rheumatic Diseases

124

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Section: Discussionmentioning

confidence: 99%

Genetics of Behcet disease inside and outside the MHC

Meguro

Inoko

Ôta

et al. 2009

Annals of the Rheumatic Diseases

124

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“…14 Likewise, Cengiz reported that the serum IgE concentrations were greater patients with Behcet's disease than those in controls, and the serum IgE levels were positively correlated with disease duration. 15 In our study of 128 patients with acute VKH disease, 27.34% had elevated serum IgE levels. Despite similar age at onset and time from symptom onset to diagnosis, patients with elevated serum IgE levels had worse visual acuity, suggesting that elevated serum IgE may be associated with more severe acute VKH disease.…”

Section: Discussionmentioning

confidence: 58%

Elevated Serum Immunoglobulin E Levels are Associated with the Severity of Newly Diagnosed, Acute Vogt–Koyanagi–Harada Disease

Zhang

Zhu

et al. 2021

Current Eye Research

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Objective: To investigate the correlation between serum immunoglobulin E (IgE) levels and severity of Vogt-Koyanagi-Harada (VKH) disease. Methods: The medical records of patients with VKH disease between 2015 and 2020 were reviewed. Serum immunoglobulins (IgA, IgE, IgG, and IgM), tumor necrosis factor α (TNFα) and C-reactive protein (CRP) were measured. Patients were divided into IgE-positive (IgE ≥ 100 IU/mL) and IgE-negative (IgE < 100 IU/mL) groups. The best-corrected visual acuity (BCVA) and macular morphologic characteristics including foveal thickness (FT), serous retinal detachment (SRD), sensory retinal thickness (SRT), central foveal thickness (CFT), cube volume (V), and cube average thickness (AT) were determined in patients in both groups. Results: Of 128 patients included in the study, 35 (27.34%) patients were IgE-positive, BCVA (logMAR) was worse in the IgE-positive group. The mean CRP (P= .012) and TNFα (P≤ 0.001) levels were greater in the IgE-positive group than in the IgE-negative group. Regarding macular morphologic characteristics, FT (P= .010), SDR (P= .004), CFT (P= .008), V (P= .013), and AT (P= .006) were significantly greater in the IgEpositive group than in the IgE-negative group. Conclusions: Elevated serum IgE levels were associated with more severe macular changes in patients with VKH disease. These findings suggest that IgE may be involved in the progression of VKH disease.

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“…Cengiz reported that sT IgE concentrations were significantly higher in patients with BD than in the control group. He pointed out that there was a positive correlation between serum IgE concentrations and the duration of the disease 14 . Dinc et al .…”

Section: Discussionmentioning

confidence: 99%