Serum HDL-C levels, log (TG/HDL-C) values and serum total cholesterol/HDL-C ratios significantly correlate with radiological extent of disease in patients with community-acquired pneumonia

Changes in cholesterol level correlate with the course of pulmonary nontuberculous mycobacterial disease

“…The cholesterol level of TB patients was lower than that of healthy controls (35), and a cholesterol-rich diet accelerated the bacteriologic sterilization of sputum cultures in patients with pulmonary tuberculosis (10). In patients with severe trauma, persistence of hypocholesterolemia indicates a progressive organ/ metabolic dysfunction (36).…”

Serum total cholesterol, HDL-C and LDL-C concentrations significantly correlate with the radiological extent of disease and the degree of smear positivity in patients with pulmonary tuberculosis

“…Correlations between acute phase reactants and serum HDL-C concentrations and cytokines and serum HDL-C concentrations were shown [14,19,20]. Correlations between DRED and serum lipid concentrations were also shown in community-acquired pneumonia [14].…”

“…In particular, in pneumonia and in inflammatory disorders, such as sarcoidosis, decrease in serum HDL-C concentrations was also shown [14][15][16][17][18]. Correlations between acute phase reactants and serum HDL-C concentrations and cytokines and serum HDL-C concentrations were shown [14,19,20].…”

“…In general, a marked decrease in serum high-density lipoprotein cholesterol (HDL-C) concentrations was shown during infection and/or inflammation in several studies [11][12][13][14]. In particular, in pneumonia and in inflammatory disorders, such as sarcoidosis, decrease in serum HDL-C concentrations was also shown [14][15][16][17][18].…”

“…We also hypothesized the existence of a correlation between other serum lipid concentrations and DRED in PTB patients since correlations between acute phase reactants and various serum lipid concentrations as well as between cytokines and serum lipid concentrations have been demonstrated [14,19,20].…”