Serum Gm system in liver cirrhosis and hepatoma

Abstract

Serum Gm polymorphism was studied in 69 patients with liver cirrhosis, in 64 with liver cirrhosis plus hepatoma, in 40 with hepatoma without evidence of cirrhosis, and in 256 controls. The distribution of Gm factors in liver patients differed from that in the control group, this difference apparently being due to the distribution in cirrhosis patients negative for HBsAg and anti-HBs. Furthermore, significantly more heterozygous Gm individuals were found in this group of patients than in the control group. Thus it appears that Gm heterozygous individuals are prone to develop cryptogenic cirrhosis under the influence of other, as yet undetermined factors.

GC and C3 Serum Groups in Ulcerative Colitis

“…Among other factors, infection, allergy to dietary components and immune responses to bacterial or self-antigens have been implicated. Some serum protein groups (Hp, GC, C3, Gm, Inv) have been already studied in our department and some interest ing associations with peptic ulcer, gastric can cer, colon cancer and liver diseases have been found [2][3][4][5][6].…”