Serum glial fibrillary acidic protein as a marker of brain damage in patients after carotid endarterectomy

Iłżecki, Marek; Przywara, Stanisław; Iłżecka, Joanna; Terlecki, Piotr; Grabarska, Aneta; Stepulak, Andrzej; Dave, Shawn; Zubilewicz, Tomasz

doi:10.5603/aa.2016.0001

Cited by 2 publications

(4 citation statements)

References 20 publications

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“…According to the latest classification, there are three main types of scleroderma: diffused scleroderma (dSSc), limited scleroderma (lSSc) and scleroderma without sclerosis (SSc sine sclerodema, SSSC) [4]. In its limited form, systemic sclerosis skin changes are confined to the acral parts of the body (hands, feet, face).…”

Section: Introductionmentioning

confidence: 99%

“…The general prognosis for patients with dSSc is poor, with a ten-year survival rate in up to 74% of cases [5,6]. SSSC is a rare form of the disease in which vascular and fibrotic damage to the internal organs is present (similar to lSSc), but without cutaneous sclerosis [4,7].…”

Section: Introductionmentioning

confidence: 99%

“…A further significantly important test in SSc diagnostics is NVC. This non-invasive method uses a magnifying technique in order to evaluate the morphology of the capillaries of the nail bed, where the vessels are most visible owing to their parallel course against the skin surface [22]. It has been established that changes in NVC can be present in patients with Raynaud's phenomenon, even without any other clinical presentation of SSc for several years.…”

Section: Introductionmentioning

confidence: 99%

“…They are characterized by different evaluation of a few elements such as: enlarged/ gigantic vessels (loops), distribution of the vessels, presence of haemorrhages or oedema, avascular regions and multiple branched capillaries [ Fig. 7] [22].…”

Section: Introductionmentioning

confidence: 99%

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Potential occupational and environmental factors in SSc onset

Walecka¹,

Roszkiewicz²,

Malewska³

2018

Ann Agric Environ Med.

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Introduction and objective. Systemic sclerosis [SSc; scleroderma] is a rare, connective tissue disorder affecting all organs and systems. The primary feature of this disease is a chronic, progressive fibrosis due to excessive production of collagen and other components. There are two subsets of systemic sclerosis: 1) diffused SSc (dSSc), 2) limited SSc (lSSc) and 3) scleroderma without sclerosis (SSSC). The presented review is an attempt to summarize recent data regarding environmental and occupational factors in SSc onset. State of knowledge. There are many factors to be taken under consideration with SSc onset, although a strong correlation has been established for only a few. The most distinct factors are: crystalline silica and organic solvents (such as white spirit, aromatic, aliphatic-chain, chlorinated solvents, ketones, welding fumes). For other factors, which include abstestos, air pollution, other chemicals, silicone breast implants, tobacco smoking, drug reactions, diet influence and exposure to heavy metals, the jury is still out, and their position in SSc onset needs further studies. Conclusions. Although the pathogenesis of scleroderma remains unclear, there is a marked correlation between the onset of SSc and certain environmental or occupational factors.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Potential occupational and environmental factors in SSc onset

Walecka¹,

Roszkiewicz²,

Malewska³

2018

Ann Agric Environ Med.

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Usefulness of selected laboratory markers in stroke diagnosis

et al. 2019

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Strokes and their complications are major clinical and social problems. Stroke diagnosis is limited to clinical and imaging evaluation – mainly by computed tomography (CT), which is particularly low sensitive to early ischemic stroke. Due to diagnostic problems, there are many studies conducted to find a laboratory marker of stroke, which can play similar role to troponins in the diagnosis of acute coronary syndrome. The aim of this article is to review scientific research in which the usefulness of potential stroke markers was assessed. Among analyzed parameters there are: inflammatory mediators (CRP, IL-1, IL-6, TNF– α, MCP-1, MMP-9), neural tissue markers (S100B protein, NSE, GFAP), coagulation and fibrinolysis components (vWF, D-dimer) and other markers – BNP, NT-proBNP, and osteoprotegerin. Some studies show the potential of laboratory markers in the differential diagnosis of the type of stroke, predicting the risk of mortality, or in patient’s condition assessment but yet none of the markers fulfill the criteria of a diagnostic test in stroke.

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Serum glial fibrillary acidic protein as a marker of brain damage in patients after carotid endarterectomy

Abstract: Introduction.

Cited by 2 publications

References 20 publications

Potential occupational and environmental factors in SSc onset

Potential occupational and environmental factors in SSc onset

Usefulness of selected laboratory markers in stroke diagnosis

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