Serum‐free medium for recombinant protein expression in insect cells
Shao‐Lei Geng,
Ying Zou,
Zhi‐Yuan Bai
et al.
Abstract:The baculovirus expression vector system (BEVS) has been widely used to produce recombinant proteins because of several advantages, such as eukaryotic post‐translational modifications similar to those in mammalian cells, high expression levels and safety, and large gene capacity. Usually, insect cell culture requires 5%‒10% fetal bovine serum, which has many adverse effects, including high cost, heterogeneity between batches, complex composition, and pollution risks. Therefore, serum‐free medium (SFM) is indis… Show more
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