“…Physical examination will often show hepatosplenomegaly, lymphadenopathy, pallor and petechiae if pancytopenia is present, and, in some patients, mucous membrane ulcerations as well as skin ulcers, nodules, or molluscum-like papules (50,104,119). Laboratory studies reveal elevated alkaline phosphatase levels, pancytopenia, an increased Westergren sedimentation rate, elevated C-reactive protein levels, high lactate dehydrogenase levels, and increased ferritin expression, none of which are specific for disseminated histoplasmosis but all of which are highly suggestive of this diagnosis in the appropriate patient (16,50,68). Hypercalcemia occurs uncommonly and is similar to that described for a number of other granulomatous diseases (90).…”