Serum enzymes in disease.XIV. Abnormality of levels of transaminases and glycolytic and oxidative enzymes and of liver functions as related to the extent of metastatic carcinoma of the liver

A general review of research into the biochemical aspects of human cancer shows that certain areas of study have been fruitful, both from a diagnostic point of view and as a contribution to the understanding of human neoplastic processes. But there have been other sectors which were ushered in with great promise and a bright future, only to fade away and lose their specificity for cancer as further investigations proceeded. In illustration, several areas are discussed in some detail: (1) a general blood test for early cancer; (2) enzyme procedures in cancer; (3) the steroid discriminant in breast cancer; and (4) the carcinoembryonic test in colon‐rectal cancer. In general, some of the most common types of cancer have received little biochemical or other basic science study, whereas rare and esoteric tumors have been the subject of elegant and detailed investigations. The reason for this is brief discussed, and a plea is made for the study of the biochemical and other basic aspects of those human organs which are the sites of the common cancers in man, before and after appearance of neoplastic change.

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Serum enzymes in disease.XIV. Abnormality of levels of transaminases and glycolytic and oxidative enzymes and of liver functions as related to the extent of metastatic carcinoma of the liver

Cited by 20 publications

References 62 publications

Needle Biopsy in Differential Diagnosis of Acute Liver Disease

Needle Biopsy in Differential Diagnosis of Acute Liver Disease

The Recognition of Hepatic Metastases Through Radioisotope Color Scanning

Reflections on biochemical aspects of human cancer.The Lucy Wortham James Lecture

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