Serum Electrolytes in Cataract Patients with and without Diabetes Mellitus

Adiga, Usha; Harris, Adline

doi:10.9734/ijbcrr/2017/36813

Cited by 4 publications

(2 citation statements)

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“…As reported by Adler, disturbances in aqueous humor electrolyte levels may lead to cataract formation (Adler 7 ). We found significant elevations in serum and aqueous humor sodium levels in diabetic cataract patients, consistent with previous research linking raised serum sodium to cationic imbalances and cataractogenesis (Adler; 7 Adiga et al 14 ).…”

Section: Discussionsupporting

confidence: 92%

Exploring electrolyte imbalances in cataractogenesis: A comparative analysis of sodium and potassium levels in diabetic and non-diabetic patients

Beatrice Choppara,

Irigu Vijay Kumar,

Aradhana Badam

et al. 2024

Asian J Med Sci

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Background: Cataract, a major cause of treatable blindness accounting for 80% of cases, arises from a complex etiology involving various factors. Diabetes notably expedites cataract development, and its potential interaction with electrolyte imbalances further enhances our understanding. Aims and Objectives: This study aimed to explore the concentrations of electrolytes, specifically sodium (Na⁺) and potassium (K⁺), in both serum and aqueous humor, and their potential implications in the pathogenesis of cataracts among individuals with diabetes. Materials and Methods: A comprehensive observational study encompassed a cohort of 100 cases, equally divided into diabetic and non-diabetic cataract patients. Gender distribution and age groups were established, focusing on individuals aged 40 years and above. Serum sodium (Na⁺) and potassium (K⁺) levels were compared against reference ranges, and statistical analyses included an unpaired Student’s t-test and the Statistical Package for the Social Sciences 20 software. Results: Among diabetic cataract patients, serum sodium levels were notably elevated (149.2147±2.71 meq/L) compared to non-diabetic counterparts (145.04±2.25 meq/L), demonstrating high significance (P<0.001). Similarly, diabetic patients exhibited a marginal increase in serum potassium (4.1919±0.5011) in contrast to non-diabetic patients (4.1264±0.5124), with a non-significant P-value (P<0.5). Aqueous humor analysis revealed a substantial rise in both sodium and potassium levels among diabetic cataract cases, demonstrating high significance (P<0.001). Conclusion: This study presents compelling evidence of distinct electrolyte profiles, particularly sodium and potassium, between diabetic and non-diabetic cataract patients. Elevated serum and aqueous humor sodium levels in diabetics suggest a potential contributory role in cataractogenesis.

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Section: Discussionsupporting

confidence: 92%

Exploring electrolyte imbalances in cataractogenesis: A comparative analysis of sodium and potassium levels in diabetic and non-diabetic patients

Beatrice Choppara,

Irigu Vijay Kumar,

Aradhana Badam

et al. 2024

Asian J Med Sci

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“…Serum sodium level should be normal to keep the water electrolyte level equilibrated in the lens membrane, which is in charge of the permeability of the lens. (18) Low serum calcium levels in senile cataract patients were obtained in many previous studies, which match our results. (12) (2.1%) of the senile cataract patients were diagnosed with low serum sodium level in compression with the control.…”

Section: Discussionsupporting

confidence: 92%

The Effect of Imbalanced Levels of Some Serum Biochemical Elements on Senile Cataract Formation

Zeina M. Alsabti,

Marwan Talib Joudah,

Wisam Talib Joudah

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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Background: Cataract is the clouding of lens which subsequently may impair vision. The main subtypes of senile cataract are cortical, posterior sub-capsular and nuclear sclerosis. Electrolyte disturbance has been linked with the development of age related cataract. Aim of the Study:To assess the correlations between the levels of the blood biochemical elements (Ca ++ , Na + , K + , Cl -) and the formation of senile cataract.Patients & Method: Blood samples of 35 patients of cataract and 35 of non-cataract/ healthy people have been analyzed for calcium and electrolytes levels, all cases were female whose age ranged between (50 -70 years). (5 mL) of blood was taken from the patients' veins for the study. The serum was separated of each sample by a centrifuge at (4000) rpm for (4 min) and used for the mentioned biochemical exams. (FUJIFILM/ DRI-CHEM NX500i) biochemical analyzer was utilized in the study. The results were obtained directly from the analyzer. Results:In cataract patients group, there was a significant variations in calcium level (high, normal, and low) as well as sodium level (low and normal) compared to the control. There was no significant differences in the level of (K + and Cl -) between two groups. Conclusion:In the current study, there was a significant differences in calcium and sodium level in cataract patients group compared to the control. These variations might be one of many factors that contribute in the formation of cataract.

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Correlations Between Renal Biomarkers and the Treatment Outcomes in Diabetes: Ophthalmic Aspects

Tsai

Lai

Lee

et al. 2022

Biomarkers in Diabetes

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Serum Electrolytes in Cataract Patients with and without Diabetes Mellitus

Cited by 4 publications

References 0 publications

Exploring electrolyte imbalances in cataractogenesis: A comparative analysis of sodium and potassium levels in diabetic and non-diabetic patients

Exploring electrolyte imbalances in cataractogenesis: A comparative analysis of sodium and potassium levels in diabetic and non-diabetic patients

The Effect of Imbalanced Levels of Some Serum Biochemical Elements on Senile Cataract Formation

Correlations Between Renal Biomarkers and the Treatment Outcomes in Diabetes: Ophthalmic Aspects

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