2020
DOI: 10.1186/s42358-020-00156-2
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Serum defensin levels in patients with systemic sclerosis

Abstract: Background Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and lung as well as involvement of kidney, gastrointestinal system and heart. Aetiology and exact mechanism of disease is poorly understood. The association between antimicrobial peptides (AMPs) and other diseases such as idiopathic pulmonary fibrosis, diffuse panbronchiolitis, pulmoner alveolar proteinosis and psoriasis have been reported. A small number of studies have examined the role of AMPs on a… Show more

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Cited by 2 publications
(1 citation statement)
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“…Alpha defensins have been implicated in a range of inflammatory conditions, including inflammatory bowel syndrome, Bechet disease, systemic sclerosis, atherosclerosis, obesity, acute lung injury, and diabetes. 14 , 15 , 16 , 17 , 18 , 19 The current study specifically investigates the involvement of alpha defensin in the pathomechanism of MUHNW phenotype.…”
Section: Introductionmentioning
confidence: 99%
“…Alpha defensins have been implicated in a range of inflammatory conditions, including inflammatory bowel syndrome, Bechet disease, systemic sclerosis, atherosclerosis, obesity, acute lung injury, and diabetes. 14 , 15 , 16 , 17 , 18 , 19 The current study specifically investigates the involvement of alpha defensin in the pathomechanism of MUHNW phenotype.…”
Section: Introductionmentioning
confidence: 99%