Serum cytokine levels and periodontal parameters in ankylosing spondylitis

Abstract

The results of present study suggest that bleeding on probing was the only different periodontal parameter between the AS and the control group, and the periodontal status of patients with AS may be affected by IL-6 levels.

Chronic Periodontitis Is Associated With Spinal Dysmobility in Patients With Ankylosing Spondylitis

“…With all case definitions, there was no association between CP and AS. CP was more prevalent in the control group (50.0%) than in the group of Pischon et al (22.9%) when CP was classified by the same definition, 10 but when the criteria used in the study by Sezer et al 11 was applied, the prevalence in the present controls (25.0%) was comparable (29.2%). The different CP prevalence is likely the result of exclusion criteria; Pischon et al 10 excluded controls receiving periodontal treatment within the past 3 versus 6 months in this study.…”

“…Patients with AS reported more risk factors than controls, such as fewer dental visits within the previous 12 months and lower daily toothbrushing frequency, but the P. gingivalis carriage was the most powerful independent risk factor for CP. The strong confounder was not evaluated in the previous studies as comprehensively as this study 10–12 …”

“…CP prevalence variation in various studies is, in part, attributable to varying case definitions 32 . The previous studies on the association between AS and CP used a different definition of CP, making direct comparisons impossible 10–12 . A strength of the present study is that comprehensive full‐mouth examinations were performed and multiple definitions were used to avoid definition‐dependent bias.…”

“…In this context, CP may provide a microbial reservoir affecting the development and clinical outcomes in AS. A few studies have investigated the association between AS and CP 10–12 . Two cross‐sectional studies reported contradictory results regarding the association between CP and AS 10 , 11 .…”

“…A few studies have investigated the association between AS and CP 10–12 . Two cross‐sectional studies reported contradictory results regarding the association between CP and AS 10 , 11 . The study by Pischon et al 10 found an increased prevalence of CP in patients with AS, whereas no association was observed between AS and CP in the study of Sezer et al 11 A population study found higher CP rates in prediagnosed patients with AS than controls 12 .…”