Serum copper and zinc concentrations in a representative sample of the Canarian population

Romero, Carlos Dı́az; Sánchez, Patricia Henrı́quez; Blanco, F. López; Rodrı́guez, Elena Rodrı́guez; Serra-Majem, Lluís

doi:10.1016/s0946-672x(02)80032-3

Cited by 48 publications

(49 citation statements)

References 29 publications

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“…In our population, we did not observe gender differences for Zn status, which is in line with the similar findings in a number of studies (Rukgauer et al, 1997;Paik et al, 1999;Diaz Romero et al, 2002). However, Schumacher et al (1994) reported a higher serum mean Zn concentration in female subjects.…”

Section: Discussionsupporting

confidence: 92%

Zinc intake and status in middle-aged and older European subjects: the ZENITH study

et al. 2005

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Objective: Inadequate intakes of micronutrients in elderly negatively affect the nutritional status. Zinc is an essential micronutrient in the elderly, especially in relation to its impact on immune function, bone mass, cognitive function and oxidative stress. However, data are lacking on zinc intake and status during normal ageing. In this study, we evaluate the intake and status of zinc in late middle-aged and older free-living subjects. Design: Dietary zinc intake and zinc status in 188 middle-aged subjects from Clermont-Ferrand (Fr) and Coleraine (UK), and in 199 older subjects from Grenoble (Fr) and Roma (It) were assessed at the entry in the ZENITH study. Results: In relation to the zinc RDA for people older than 55 y, zinc intakes in most of the middle-aged and older subjects (more than 96%) in the present study were adequate. Older people had significantly lower (Po0.01) energy intakes as compared to middle-aged. Zinc intake expressed per MJ was also significantly (Po0.01) higher in older people compared to middle-aged. Erythrocyte and urinary zinc concentrations were significantly (Po0.001) higher in middle-aged subjects compared to older ones. The prevalence of biological Zn deficiency in free-living ageing European people was low (o5%). Conclusion:The results of the present study showed a relatively low prevalence of zinc deficiencies in healthy free-living late middle-age and older subjects. These results should be useful for health professionals to have reference data on zinc intake and status for a healthy ageing.

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Section: Discussionsupporting

confidence: 92%

Zinc intake and status in middle-aged and older European subjects: the ZENITH study

et al. 2005

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“…This finding is in accordance with the study in India with the mean 83.12±12.29 µg/dl and 106.68±4.11 µg/dl of CD4 T-cells count < 200/ µl and CD4 cell count >500 cell/ µl respectively [29]. In the current study, 30.6% of low serum zinc concentration was observed in those study participants who had a CD4+ T-cell count < 200 cells/µg while 25% of low serum zinc concentration were observed in those group who had a CD4+ T-cell count >500 cells/µl.…”

Section: Discussionsupporting

confidence: 93%

“…Demographic variables such as sex, residence location, marital status, monthly income and level of education were not implicated as determinants for serum zinc deficiency among the study participants. This similar finding has been reported by Visser et al, (2003), Diaz Romero et al, (2002) [23,29].…”

Section: Discussionsupporting

confidence: 91%

Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia

Ademasu¹,

Kerisew²,

Nibret³

et al. 2014

IJNFS

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Abstract:Background: Among several trace elements, zinc is a micronutrient that has a very significant role in maintaining immune function. Studies investigating trace elements status in people living with HIV/AIDS are few in Ethiopia. Hence, the present study was undertaken to investigate the concentration of serum zinc among sex and age matched pre ART and on ART adults. Methods: A cross-sectional study was conducted among 150 people living with HIV/AIDS (75 pre -ART and 75 on -ART) adults. Concentrations of zinc from serum were measured using fully automated flame atomic absorption spectrophotometer. CD4 + T-cell count, CD8 + T-cell count, hemoglobin determination, and Body Mass Index (BMI) were performed to evaluate the clinical status of study participants. Results: Serum zinc deficiencies were observed in 46 (30.7%) study participants. In multivariate logistic regression analysis, pre-ART study participants were nearly four times more likely at risk of serum zinc deficiency than on-ART study participants (AOR=3.56, 95% CI=1.52 to 8.32). Similarly, the odds of being serum zinc deficient were three times more in undernourished study participants than nourished study participants (AOR=2.61, 95% CI=1.02 to 6.67). Conclusion: A relatively high percentage of study participants had serum zinc deficiency. Early evaluation of serum zinc deficiency and zinc supplementation along with anti-retroviral treatment should be considered for pre-ART and under nourished adult people living with HIV/AIDS.

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“…Nonetheless, regional differences in dietary patterns including seasoning, may modulate zinc bioavailability because of the complex combination of nutrients and non-nutritive compounds present in diet that interact with zinc (Lonnerdal, 2000;Martin, 2001;Winichagoon, 2008). Regional differences have also been reported in European countries (Kvicala and Jiranek, 1999;Diaz Romero et al, 2002). However, the positive association between zinc concentrations and volcanic soils, suggested as an explanation in Canarian islands (Diaz Romero et al, 2002) was not observed in SU.VI.MAX.…”

Section: Discussionmentioning

confidence: 83%

“…Regional differences have also been reported in European countries (Kvicala and Jiranek, 1999;Diaz Romero et al, 2002). However, the positive association between zinc concentrations and volcanic soils, suggested as an explanation in Canarian islands (Diaz Romero et al, 2002) was not observed in SU.VI.MAX.…”

Section: Discussionmentioning

confidence: 83%

Determinants of serum zinc concentrations in a population of French middle-age subjects (SU.VI.MAX cohort)

et al. 2010

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Background/Objectives: Few studies have been conducted on determinants of serum zinc concentration, especially in France. The aim of this study was to investigate the relationships between serum zinc concentrations, and age, education, living area and life style in a large sample cohort of French adults. Subjects/Methods: Blood samples were collected after 12-h fasting in French adults (7448 women, 35-65 years old and 4926 men, 45-65 years old) participating to the SUpplementation in AntioXidant VItamins and Minerals cohort at enrolment. Serum zinc was determined by flame atomic absorption. Results: Serum zinc concentration was lower in women (mean: 12.9 mmol/l, 95% confidence interval: 9.2-16.6 mmol/l) compared with men (mean: 13.4 mmol/l, 95% confidence interval: 9.7-17.1 mmol/l, Po0.0001). In total, 10% of the women showed serum zinc values o10.7 mmol/l and 10% of the men showed serum zinc values o11.3 mmol/l. Age was negatively associated with serum zinc only in men (P ¼ 0.001). In women, a positive association between smoking and serum zinc concentration (P ¼ 0.0003), and a negative relationship between highest education level and serum zinc concentration (P ¼ 0.01) were observed. With regard to geographical areas, the highest serum zinc concentrations were found in the Center, and the lowest in the Southwest of France for both men and women. The association between serum zinc concentrations and food categories or macronutrient intake disappeared after stratifying by gender. Conclusions: Age, gender and geographic area seem the main determinants of serum zinc concentrations in this study.

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Serum copper and zinc concentrations in a representative sample of the Canarian population

Cited by 48 publications

References 29 publications

Zinc intake and status in middle-aged and older European subjects: the ZENITH study

Zinc intake and status in middle-aged and older European subjects: the ZENITH study

Serum Zinc Deficiency and Associated Factors among Pre-ART and on-ART Adults at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia

Determinants of serum zinc concentrations in a population of French middle-age subjects (SU.VI.MAX cohort)

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