1991
DOI: 10.2165/00003088-199120030-00001
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Serum Concentration Monitoring of Cardiac Glycosides

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Cited by 18 publications
(1 citation statement)
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“…It should also be noted that the trough plasma levels of digoxin after repeated once‐daily oral dosing in patients with Parkinson’s disease with 0.125 mg digoxin obtained in this study are within the same range quoted for patients in the literature [ 7]. Changes in trough levels of digoxin are believed to be the most reliable way of assessing steady‐state concentrations of digoxin [ 8, 9], and therefore the clinical significance of an interaction. Changes in C max are too readily influenced by other factors.…”
Section: Discussionsupporting
confidence: 75%
“…It should also be noted that the trough plasma levels of digoxin after repeated once‐daily oral dosing in patients with Parkinson’s disease with 0.125 mg digoxin obtained in this study are within the same range quoted for patients in the literature [ 7]. Changes in trough levels of digoxin are believed to be the most reliable way of assessing steady‐state concentrations of digoxin [ 8, 9], and therefore the clinical significance of an interaction. Changes in C max are too readily influenced by other factors.…”
Section: Discussionsupporting
confidence: 75%