“…Moreover, CA 125 concentrations are elevated in women with benign gynaecologic conditions, including ovarian cysts, endometriosis and uterine fibroids, which are part of the differential diagnosis for ovarian cancer (Mogensen, 1992;Cannistra, 1993;Mackey and Creasman, 1995). In some cases, women with hepatic disease, renal failure, pancreatitis or other conditions may have elevated CA 125 making the usefulness of CA 125 as a marker for early detection limited (Bastani and Chu, 1995;Devarbhavi et al, 2002). In recent years, several serum markers have been identified and explored as possible adjuncts to CA 125 screening.…”