Serum anti-Müllerian hormone levels during estrus and diestrus in mares

Abstract

Anti-Müllerian hormone (AMH) is a homodimeric glycoprotin secreted by granulosa cells in postnatal females. AMH plays an important role in follicle recruitment. The aim of the study was to analyse AMH concentrations under the guidance of circulating estradiol and progesterone levels in mares. The study was conducted on 25 non-lactating mares with regular estrous cycles. Blood samples were collected during estrus and diestrus to analyse estradiol, progesterone and AMH concentrations. Estradiol and progesterone concentrations were significantly different (P < 0.001) between estrus and diestrus. AMH concentrations in estrus were significantly higher than those in diestrus (P < 0.05). According to the authors’ knowledge, this is the first report to suggest that the sexual cycle stage affects AMH concentrations in mares. Further investigations are needed to reveal factors affecting the AMH production and secretion pattern throughout the sexual cycle.

Anti-Müllerian Hormone and OPU-ICSI Outcome in the Mare

“…Results from various studies regarding the consistency of AMH concentrations throughout the estrous cycle are inconclusive. Almeida et al [35] found no significant difference in AMH concentration measured three times a week throughout one inter-ovulatory period in six normal cyclic mares, while Dal et al [59] observed that AMH concentrations were significantly higher in estrus than in diestrus in 25 mares. As our study was designed retrospectively, from a clinical point view, and since AMH concentrations appear to be repeatable within individual normal cyclic mares [35,41], blood samples were obtained on the day of the OPU session, regardless of the day of the estrous cycle.…”

Anti‐Müllerian hormone concentrations in female rabbits and its relation to spay status, pseudopregnancy and ovarian follicle numbers

“…In the bitch and the queen, significant fluctuations of serum AMH concentrations during the oestrous cycle were reported, albeit limited by breed influences and high individual variations (Flock et al, 2019; Walter et al, 2019). In horses, while one study described no significant changes in AMH levels during the oestrous cycle or pregnancy (Almeida et al, 2011), a recent study suggested increased AMH concentrations in oestrous mares compared with mares in dioestrus (Dal & Kasikci, 2020). In most studies in cattle, no significant variations of serum AMH levels throughout oestrous cycles were described (El‐Sheikh Ali et al, 2013; Monniaux et al, 2010; Rico et al, 2009).…”