Serum albumin and prognosis in elderly patients with nonischemic dilated cardiomyopathy

Zhang, Xiaonan; Zeng, Zhigang; Mai, William; Peng, Zishan; Li, B.; Hong, Wanzi; Liu, Yaoxin; Shu, Fen; Tang, Junnan; Xu, Li‐Yan; Tan, Ning; Ma, Jinjin; Jiang, Lei

doi:10.2459/jcm.0000000000001530

Cited by 4 publications

(4 citation statements)

References 34 publications

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“…In patients with hypoproteinemia caused by disease or diet, nutritional deficiency in local skin tissues is not conducive to cell growth and wound healing. 18 In the present study, we found that Lac level was significantly associated with the occurrence of pressure ulcers. Lac is a key product of human glucose metabolism and anaerobic cell metabolism.…”

Section: Discussionsupporting

confidence: 57%

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Development of a Nomogram for Predicting the Risk of Hospital-Acquired Pressure Injuries in Patients in the Cardiovascular Intensive Care Unit

Li,

Zhang,

Shui

et al. 2023

Preprint

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PurposeHospital-acquired pressure injuries (HAPIs) increase the medical burden of patients in the cardiovascular intensive care unit (CCU). Thus, identification of CCU patients with a risk for HAPIs is important. To establish a nomogram model for predicting the occurrence of HAPIs in patients in the CCU.MethodsThis was a retrospective cohort study in patients in the CCU at our hospital who developed HAPIs between January 2023 and June 2023. Patient data were extracted from the hospital’s information management system. Risk factors for HAPIs were identified using univariate and multivariate logistic regression analyses and the screened indicators were integrated into a nomogram. The effectiveness of the nomogram was evaluated and verified using receiver operating characteristic curve and decision curve analysis (DCA).ResultsIn this study, a total of 161 patients were enrolled. Univariate logistic regression analysis showed that vasopressor use (OR=2.51, 95%CI=1.24–5.09,p=.010) and NT-proBNP (OR=2.92, 95%CI=1.45–5.92,p=.003), lactic acid (OR=9.43, 95%CI=4.15–21.41,p<.000), procalcitonin (OR=1.37, 95%CI=1.07–1.75,p=.012), D-dimer (OR=1.16, 95%CI=1.05–1.28,p= .004), and albumin (OR=0.88, 95%CI=0.81–0.95,p=.002) levels were independent risk factors for HAPIs. Multivariate logistic regression analysis showed that vasopressor use (OR=3.05, 95%CI=1.20–7.73,p=.019) and lactic acid (OR=12.05, 95%Cl=4.13–35.21,p<.000), procalcitonin (OR=1.30, 95%Cl=1.01–1.69,p=.043) and albumin (OR=0.82, 95%Cl=0.73–0.93,p=.002) levels were independent risk factors for HAPIs. The nomogram was well-calibrated and showed good discriminative ability (AUC=.87). The DCA showed a better net benefit, and the results were confirmed within the validation cohort.ConclusionThe nomogram model developed in this study showed good predictability and can identify patients at risk of developing HAPIs and aid the formulation of targeted interventions.

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Section: Discussionsupporting

confidence: 57%

“…In patients with hypoproteinemia caused by disease or diet, nutritional deficiency in local skin tissues is not conducive to cell growth and wound healing. 18…”

Section: Discussionmentioning

confidence: 99%

Development of a Nomogram for Predicting the Risk of Hospital-Acquired Pressure Injuries in Patients in the Cardiovascular Intensive Care Unit

Li,

Zhang,

Shui

et al. 2023

Preprint

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“…In the elderly with severe AS, numerous factors such as prolonged inflammation, appetite loss, decreased physical capacity, reduced muscle mass, impaired mental functions, and coexisting comorbidities often contribute to malnutrition. Hypoalbuminemia, a marker of malnutrition, is associated with increased in-hospital and long-term mortality in patients with dilated caridyomyopathy 34 . This nutritional deficiency markedly increases frailty in patients, adversely impacting their prognosis.…”

Section: Discussionunclassified

The impact of the Naples Prognostic Score on the short- and long-term prognosis of patients undergoing transcatheter aortic valve implantation

Hakgor,

Dursun,

Kahraman

et al. 2024

Journal of Cardiovascular Medicine

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Background Preoperative systemic inflammation and nutritional status have been shown to affect prognosis in patients undergoing transcatheter aortic valve implantation (TAVI). In this study, we investigated the effect of the Naples Prognostic Score (NPS), which consists of four different parameters including these two components on short- and long-term prognosis in patients undergoing TAVI. Methods In 343 patients (mean age 78.1 ± 8.4 years, 51.3% female) who underwent TAVI, the NPS score was calculated from the blood tests obtained before the procedure and the study population was divided into three according to the NPS value: those with 0 and 1 were divided into Group-1, those with 2 into Group-2, and those with 3 and 4 into Group-3. The relationship between NPS group and in-hospital adverse events and long-term survival was evaluated. Results Systolic pulmonary artery pressure, STS score, presence of chronic lung disease and being in NPS Group-3 [adjusted odds ratio (adjOR): 3.93, 95% confidence interval (CI) (1.02–15.17), P = 0.047] were found to be independent predictors of in-hospital mortality. According to the multivariate Cox-regression model, both Group-2 NPS [adjusted hazard ratio (adjHR): 4.81, 95% CI (1.09–21.14), P = 0.037] and Group-3 NPS [adjHR: 10.1, 95% CI (2.31–43.36), P = 0.002] was an independent predictor of 2-year all-cause mortality after TAVI. There was no significant difference in perioperative adverse events between the groups except for postprocedural acute kidney injury. According to receiver-operating characteristic analysis, the optimal predictive value of NPS for in-hospital and long-term mortality was 2.5. Conclusion In patients who will be candidates for TAVI, NPS is a simple and effective tool for determining both short- and long-term prognosis.

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“…The following funding statement of this paper should have appeared in this paper by Li et al 1 . This was removed in error before final publication.…”

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confidence: 99%