Serum afamin and its implications in adult growth hormone deficiency: a prospective GH-withdrawal study
Balázs Ratku,
Hajnalka Lőrincz,
Sára Csiha
et al.
Abstract:IntroductionAdult growth hormone deficiency (AGHD) is associated with a high prevalence of metabolic syndrome (MS), which contributes to the unfavorable cardiovascular risk profile in these patients. Insulin like growth factor-1 (IGF-1) is a widely used biomarker, however it does not always reflect the cardiometabolic risk and has a poor relationship with clinical efficacy endpoints. Consequently, there is an unmet need for biomarkers to monitor responses to GH-replacement. Afamin is a hormone-like glycoprotei… Show more
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