Serratus Plane Block in Breast Cancer Surgery: A Systematic Review and Meta-Analysis

Li, Zhenhao; Hong, Wei‐Jin; Guo, Xiaoliang; Li, Xinrui; Jiang, Xuan-Yu; Jiang, Yu; Luo, Sheng-Kang

doi:10.1016/j.clbc.2022.10.009

Cited by 5 publications

(2 citation statements)

References 41 publications

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“…The SAPB is a novel regional anesthetic technique for the thoracic wall that appears to be a feasible alternative to TPVB. A recent meta-analysis of 12 RCTs of moderate to high quality confirmed the efficacy and safety of SAPB compared to no regional block and its ability to be a possible alternative to TPVB for perioperative analgesia in breast cancer surgery [14]. The application of the SAPB significantly relieves post-operative pain in breast surgery and reduces intraoperative and post-operative consumption of analgesics.…”

Section: Discussionmentioning

confidence: 97%

Effects of Adding Dexamethasone Plus Ketamine to Bupivacaine for Ultrasound-guided Serratus Plane Block as Analgesia in Major Breast Surgery: A Randomized, Double-blind Trial

Bakeer,

Abdou,

Abdelhaleem

et al. 2024

Open Access Maced J Med Sci

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BACKGROUND: Post-operative pain after mastectomy is associated with poor recovery, prolonged hospital stays, and increased liability for chronic persistent pain. AIM: This work aimed to test the analgesic efficacy of adding ketamine to a dexamethasone bupivacaine combination in ultrasound-guided serratus anterior plane block (SAPB) in patients undergoing modified radical mastectomy (MRM). METHODS: This randomized, double-blind trial included 60 females aged 20–60 undergoing MRM. They were randomized into two groups: Group DB (n = 30) received SAPB using 30 ml of bupivacaine 0.25% and dexamethasone 4 mg. Group KD (n = 30) received the same block with the addition of ketamine 50 mg. RESULTS: The time to the first analgesic request was significantly delayed in Group KD than in Group DB (p < 0.001). The number of patients requiring morphine and its total consumption during the first 24 post-operative hours in Group KD were significantly less than in Group DB (p = 0.001 and p < 0.001, respectively). Visual Analog Scale scores at rest and movement at 4, 6, 8, 10, 12, and 18 h were significantly lower in Group KD than in Group DB. CONCLUSIONS: Adding ketamine to bupivacaine plus dexamethasone in ultrasound-guided SAPB is associated with better analgesic outcomes in patients undergoing MRM, including prolonged duration of analgesia and decreased post-operative morphine consumption and pain scores at rest and movement.

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Section: Discussionmentioning

confidence: 97%

Effects of Adding Dexamethasone Plus Ketamine to Bupivacaine for Ultrasound-guided Serratus Plane Block as Analgesia in Major Breast Surgery: A Randomized, Double-blind Trial

Bakeer,

Abdou,

Abdelhaleem

et al. 2024

Open Access Maced J Med Sci

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“…When compared to TPVB, SAPB was not worse for the all evaluated parameters. 48 Similarly, in a meta-analysis evaluating the efficacy of SAPB in thoracic surgery, SAPB reduced both pain scores and postoperative 24-hour opioid consumption, in addition, there was a lower incidence of PONV in the SAPB group. 51 …”

Section: Breast and Thoracic Surgerymentioning

confidence: 96%

The Shining Star of the Last Decade in Regional Anesthesia Part-I: Interfascial Plane Blocks for Breast, Thoracic, and Orthopedic Surgery

Ahişkalıoğlu¹,

Yayık²,

Çelik³

et al. 2023

Eurasian J Med

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Regional anesthesia has benefits beyond just treating acute postoperative pain. Interfascial plane blocks, which have been very popular with ultrasound in recent years, function primarily by administering a high volume of a local anesthetic to the fascial plane. Contrary to traditional peripheral nerve blocks, the targeted nerve or structure in interfacial plane blocks is not fully defined, and the indications have not been fully revealed yet. Anatomical, cadaveric, and radiological studies show how effective the interfascial plane blocks play a role. This review focuses on the benefits, techniques, indications, and complications of interfascial plane blocks in the context of breast, thoracic, and orthopedic surgery.

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Regional Anesthesia Techniques for Breast Cancer Surgeries—A Narrative Review

Sethuraman

2024

Indian J Surg Oncol

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Serratus Plane Block in Breast Cancer Surgery: A Systematic Review and Meta-Analysis

Cited by 5 publications

References 41 publications

Effects of Adding Dexamethasone Plus Ketamine to Bupivacaine for Ultrasound-guided Serratus Plane Block as Analgesia in Major Breast Surgery: A Randomized, Double-blind Trial

Effects of Adding Dexamethasone Plus Ketamine to Bupivacaine for Ultrasound-guided Serratus Plane Block as Analgesia in Major Breast Surgery: A Randomized, Double-blind Trial

The Shining Star of the Last Decade in Regional Anesthesia Part-I: Interfascial Plane Blocks for Breast, Thoracic, and Orthopedic Surgery

Regional Anesthesia Techniques for Breast Cancer Surgeries—A Narrative Review

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