Serratia marcescens corneal ulcer as a complication of orthokeratology

Chen, Ko Hua; Kuang, Tung-Mei; Hsu, Wen-Ming

doi:10.1016/s0002-9394(01)00931-x

Cited by 57 publications

(37 citation statements)

References 5 publications

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“…1 To our knowledge, corneal ulcer as a complication of orthokeratology has only been described once before, when the organism responsible was Serratia Marcescens. 2 Unfortunately, no organism was identified in this case. Orthokeratology has also been associated with filtering bleb infection in a myopic patient with glaucoma.…”

Section: Commentmentioning

confidence: 84%

Microbial keratitis following orthokeratology

Poole

Frangouli

Ionides

2003

Eye

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Section: Commentmentioning

confidence: 84%

Microbial keratitis following orthokeratology

Poole

Frangouli

Ionides

2003

Eye

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“…Em outras palavras, a ortoceratologia (ortoK) é um procedimento não cirúrgico que permite o remodelamento ou aplanamento corneano através de lentes de contato, a fim de reduzir os erros refrativos (4,6,8,9,11,12,14,15) .…”

Section: Ortoceratologia Atual: Definições E Conceitosunclassified

Novos conceitos em modelamento corneano

Brocchetto

Dantas

Schor

2010

Rev. bras.oftalmol.

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RESUMOA córnea possui grande influência no processo visual. Porém é passível de deformação, tal como o aplanamento. Quando esse aplanamento é causado pelo uso de lentes de contato, chamamos de "corneal warpage". Neste caso, alguns sintomas podem ocorrer como visão embaçada com os óculos, hiperemia conjuntival, sensação de corpo estranho, etc. Pensava-se que a córnea era mais rígida e, com o tempo, percebeu-se que a córnea possui entidade viscoelástica. Podemos dizer que a córnea possui uma entidade biomecânica e que, quando sofre instabilidade, ocorrem algumas alterações, como no caso do ceratocone, onde ocorre uma degeneração progressiva corneana. Com o intuito de buscar a estabilização corneana, foi desenvolvida a técnica de "crosslink", que consiste em promover ligações covalentes entre as lamelas da córnea para torná-la mais firme e menos elástica. Outra alteração corneana pode ser induzida, de forma planejada, através do modelamento corneano com o uso de lentes de contato rígidas, com coeficiente de transmissibilidade de oxigênio (DK/L) maior. Elas são usadas somente durante o sono, não sendo necessário o seu uso diurno. Esta técnica é conhecida como Ortoceratologia e seus conceitos serão abordados neste estudo.

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“…These reverse-geometry and rigid gas-permeable contact lenses are worn overnight, thereby allowing the patient to achieve improved uncorrected visual acuity during the day (Alharbi and Swarbrick, 2003). Although the advent of this reverse-geometry contact lens design, coupled with novel rigid gas-permeable materials evidencing high oxygen transmissibility, contribute to more stable and safer effects, the inherent tight bending of the cornea and overnight wear have both been identified as risk factors for infectious keratitis (Dart, 1998;Nichols et al, 2000;Chen et al, 2001). Many reported cases of orthokeratology-associated microbial keratitis have been caused by Pseudomonas aeruginosa (Lau et al, 2003; , 2003, 2004), but Acanthamoeba is becoming recognized as one of the primary causes, as well (Xuguang et al, 2003;Hutchison and Apel, 2002;Wilhelmus, 2005).…”

Section: Introductionmentioning

confidence: 99%

Molecular characterization of Acanthamoeba isolated from amebic keratitis related to orthokeratology lens overnight wear

Jeong

Lee

et al. 2006

Korean J Parasitol

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Abstract:In an effort to characterize, on the molecular scale, the Acanthamoeba initially isolated from the cornea of an amoebic keratitis patient associated with overnight-wear orthokeratology lens in Korea, we conducted mitochondrial DNA restriction fragment length polymorphism, 18S rDNA sequencing, and drug sensitivity analyses on the isolate (KA/PE1). The patient was treated with polyhexamethylene biguanide, chlorhexidine and oral itraconazole, which resulted in resolution of the patient's ocular inflammation. The majority of the molecular characteristics of the KA/PE1 were determined to be identical, or quite similar, to those of A. castellanii Ma strain, which had been isolated also from amoebic keratitis. The risk of Acanthamoeba keratitis as a potential complication of overnight orthokeratology is briefly discussed.

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Serratia marcescens corneal ulcer as a complication of orthokeratology

Cited by 57 publications

References 5 publications

Microbial keratitis following orthokeratology

Microbial keratitis following orthokeratology

Novos conceitos em modelamento corneano

Molecular characterization of Acanthamoeba isolated from amebic keratitis related to orthokeratology lens overnight wear

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