SERPINH1 promoted the proliferation and metastasis of colorectal cancer by activating PI3K/Akt/mTOR signaling pathway
Xiao-Sheng Jin,
Lu-Xi Chen,
Ting-Ting Ji
et al.
Abstract:BACKGROUND
Serpin peptidase inhibitor clade H member 1 (SERPINH1) was initially recognized as an oncogene implicated in various human malignancies. Nevertheless, the clinical relevance and functional implications of SERPINH1 in colorectal cancer (CRC) remain largely elusive.
AIM
To investigate the effects of SERPINH1 on CRC cells and its specific mechanism.
METHODS
Quantitative real-time polymerase chain reaction, western blotting analysis, The Cancer Genome At… Show more
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