2004
DOI: 10.1093/jac/dkh250
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Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in Austria

Abstract: This rise in pneumococcal resistance to penicillin and clarithromycin, and the change in distribution of serotypes in these resistant strains, indicates that ongoing surveillance programmes are warranted, in order to be able to formulate both effective vaccination strategies and optimal antibiotic therapies.

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Cited by 11 publications
(5 citation statements)
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“…The shift could be explained by the introduction of the Spain 9V -3 clone into the country from highprevalence western European regions after the political changes in 1989, with the subsequent sharp rise in international travel. Interestingly, in results parallel to those from the Czech Republic, Buxbaum et al (2004) found serogroup 9 to have become predominant among the penicillin nonsusceptible serogroups in Austria in 1998. In contrast to the Czech Republic, this change was accompanied by a dramatic rise in penicillin resistance, which almost doubled the rate in Austria to nearly 10 %.…”
Section: Mlst Analysissupporting
confidence: 53%
“…The shift could be explained by the introduction of the Spain 9V -3 clone into the country from highprevalence western European regions after the political changes in 1989, with the subsequent sharp rise in international travel. Interestingly, in results parallel to those from the Czech Republic, Buxbaum et al (2004) found serogroup 9 to have become predominant among the penicillin nonsusceptible serogroups in Austria in 1998. In contrast to the Czech Republic, this change was accompanied by a dramatic rise in penicillin resistance, which almost doubled the rate in Austria to nearly 10 %.…”
Section: Mlst Analysissupporting
confidence: 53%
“…As published previously, resistance of S. pneumoniae to erythromycin in Austria increased from 3.2% in 1996 to 12.8% in 2007 and 9.8% in 2008 [16][17][18]. In our study, rates of erythromycinresistant S. pneumoniae isolates increased in accordance with national and international trends from 3.5% in 1997 to 18.2% in 2004 and 14.7% in 2008.…”
Section: Discussionsupporting
confidence: 89%
“…However, two possible limitations must be considered when comparing these data with previously published Austrian data. First, different inclusion criteria may have influenced divergent results compared with the study of Buxbaum et al [17]. Whilst patients below 18 years of age were excluded in their study, this group of patients accounted for the majority of patients in the current study.…”
Section: Discussionmentioning
confidence: 92%
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“…Один из перспективных препаратов данной груп пы -16 членный природный макролид джозамицин, который обладает высокой активностью в отноше нии S. pneumoniae и S. pyogenes (в т. ч. ряда штаммов, устойчивых к эритро , кларитро , рокситро и азит ромицину), а также атипичных микроорганизмов (хламидии, микоплазмы, легионеллы) [13][14][15][16][17][18][19][20][21]. По сравнению с эритромицином, джозамицин характе ризуется улучшенными фармакокинетическими параметрами [22].…”
Section: резюмеunclassified