Serotonin modulation of caudal photoreceptor in crayfish

Rodrı́guez-Sosa, Leonardo; Calderón-Rosete, Gabina; Villalobos, Mercedes Graciela Porras; Zamora, Elena Mendoza; González, Víctor Anaya

doi:10.1016/j.cbpc.2005.10.006

Cited by 13 publications

(16 citation statements)

References 62 publications

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“…The pattern of spontaneous activity and responsiveness of the caudal photoreceptor to light reported here are comparable to those described previously (Rodríguez-Sosa et al, 2006. From our results, we suggest that exogenous DA affects the spontaneous activity in the dark (Fig.…”

Section: Discussionsupporting

confidence: 91%

Dopaminergic modulation of the caudal photoreceptor in crayfish

Rodrı́guez-Sosa

Calderón-Rosete

Calvillo³

et al. 2010

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In our study we investigated the influence of dopamine (DA) on the caudal photoreceptor (CPR) in crayfish. Here we report the following: (a) the chromatographic determination of DA in the sixth abdominal ganglion (6th AG) shows a variation in the content during a 24-h cycle with the maximum value at dawn. (b) There are possibly dopaminergic neurons in the 6th AG with antityrosine hydroxylase antibodies. Immunopositive neurons (164) were located in the anterior and posterior regions of the 6th AG with the mean (± SE) diameter of their somata 23 ± 1 μm. In addition, there is immunopositive staining in axons, neuropilar fibers, and varicosities. (c) We also identified, using immunohistochemistry, 108 neurons in the sixth AG that contain dopamine D1-like receptors, with the mean (±SE) diameter of their somata 18 ± 1 μm. (d) We examined the exogenous action of DA on the electrical activity of the CPR in the isolated sixth AG by conventional extracellular-recording methods. This CPR displays spontaneous activity and phasic-tonic responses to light pulses. Topical application of dopamine to ganglia kept in the dark increased the spontaneous firing rate of the CPR, whereas the photoresponse of the CPR remained unchanged. The effect on the spontaneous activity is dose-dependent with an ED₅₀ of 33 μM, and is blocked by the dopamine D1-like antagonist SCH23390. These observations suggested that the DA is playing the role of a neurotransmitter or a neuromodulator of the CPR in the 6th AG in both species of crayfish, Procambarus clarkii and Cherax quadricarinatus.

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Section: Discussionsupporting

confidence: 91%

Dopaminergic modulation of the caudal photoreceptor in crayfish

Rodrı́guez-Sosa

Calderón-Rosete

Calvillo³

et al. 2010

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“…These are on the anterior part of the ventral side of the ganglion (Prosser, 1934;Welsh, 1934;Wilkens andLarimer, 1972, 1976). Their physiological properties and role in the behavior of the animals have been extensively studied (Larimer and Moore, 2003;Rodríguez-Sosa et al, 2006;Wilkens, 1988). This caudal photoreceptor (CPR) displays spontaneous electrical activity and phasic-tonic responses to light pulses.…”

Section: Introductionmentioning

confidence: 99%

Serotonin‐caused phase shift of circadian rhythmicity in a photosensitive neuron

Rodrı́guez-Sosa

Calderón-Rosete

Flores

et al. 2007

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In the sixth abdominal ganglion (sixth AG) of the crayfish, two photosensitive neurons are located and have been identified as caudal photoreceptors (CPRs). We have expanded our investigation on the role of 5-Hydroxytryptamine (5-HT) as a modulator of the spontaneous and light-induced activity of the CPR. We located, by using immunocytochemistry, neurons in the sixth AG that contain the 5HT1A receptor. The expression of these receptors was examined by binding assays with [3H] 8-hydroxy-2 (di-n-propylamino) tetralin ([3H(8-OH-DPAT). We examined the exogenous action of both 5HT and its agonist 8-OH-DPAT on the phase of circadian rhythms of the spontaneous electrical activity and the photoresponse of the CPR in the isolated sixth AG by conventional extracellular recording methods. Experiments were made on the adult crayfish Procambarus clarkii and Cherax quadricarinatus. Thirteen immunopositive neurons were located, principally near the ventral and dorsal surface of the sixth AG, with the mean diameter of their somata 20+/-3 microm. The specific binding data showed the presence of 5-HT1A receptors with a mean level of 22.4+/-6.6 fmol/mg of wet tissue. Spontaneous and light-induced electrical activity of the CPR showed circadian variations with their activity more intense at night than in the day. Exogenous application of 5-HT or 8-OH-DPAT causes a circadian phase-shift in electrical activity of the CPR. Taken together, these results lead us to believe the 5-HT acts as a modulator of circadian electrical activity of the CPR in the isolated sixth AG of crayfish. Moreover, it suggests that the 5-HT1A receptor participates in this modulation.

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“…Serotonin also modulates photoreceptor activity in crustaceans (Aréchiga et al, 1990;Rodríguez-Sosa et al, 2006). For example, the firing frequency of action potentials is increased in the caudal photoreceptors in crayfish upon exposure to serotonin (Rodríguez-Sosa et al, 2006).…”

Section: Speculation On the Mode Of Action Of Serotoninmentioning

confidence: 99%

“…For example, the firing frequency of action potentials is increased in the caudal photoreceptors in crayfish upon exposure to serotonin (Rodríguez-Sosa et al, 2006). It is tempting to speculate that serotonergic modulation of visual pathways changes the nature of incoming information to optic areas of the CNS.…”

Section: Speculation On the Mode Of Action Of Serotoninmentioning

confidence: 99%

Parasite-induced alterations of sensorimotor pathways in gammarids: collateral damage of neuroinflammation?

Helluy

2013

Journal of Experimental Biology

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Serotonin modulation of caudal photoreceptor in crayfish

Cited by 13 publications

References 62 publications

Dopaminergic modulation of the caudal photoreceptor in crayfish

Dopaminergic modulation of the caudal photoreceptor in crayfish

Serotonin‐caused phase shift of circadian rhythmicity in a photosensitive neuron

Parasite-induced alterations of sensorimotor pathways in gammarids: collateral damage of neuroinflammation?

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