Serotonergic and Catecholaminergic Interactions with Co‐Localised Dopamine‐Melatonin Neurones in the Hypothalamus of the Female Turkey

Kang, Seong Wook; Leclerc, B.; Mauro, Laura J.; Halawani, Mohamed E. El

doi:10.1111/j.1365-2826.2008.01804.x

Cited by 12 publications

(14 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some nuclei such as superior olivary nucleus[27–29] and dorsal nucleus of the lateral lemniscus[28]could co-localize or overlap with T-J body. Or, a relative neighboring position could be plexus of Horsley or facial motor nucleus[27, 30–33]. We also noted that no similar T-J body was found in the chicken with Golgi staining[29].…”

Section: Discussionmentioning

confidence: 99%

Specialized NADPH diaphorase membrane-related localizations in the brainstem of the pigeons (Columba livia)

Jia

Hou

et al. 2019

Preprint

View full text Add to dashboard Cite

NADPH diaphorase (N-d) is used to a histochemical identification of subgroup of neuronal cells. Beside regular intracellular N-d positivity, membrane-related positivity revealed as a specialized staining pattern in the pigeon brain stem. In the investigation of the nervous system of homing pigeons (Columba livia) with N-d staining, we found a specialized structure, which temporally was termed as N-d tubular glomerular body/structure or as T-J body related to the last name of authors. This N-d positive specialization constituted by tubular components bilaterally located in the medial to the lemniscus spinalis in the medulla oblongata. The tubular components were moderate staining. T-J body was a longitudinal oriented structure of 2400 μ m with N-d staining. N-d positive tubular components were twisted and intermingled together.Beside the young adult pigeons, T-J body s were also consistently detected in the aged pigeons. Membrane-related staining were also detected in the other rostral nuclei in the brain stem. With discussion and review of related scientific literatures, T-J body was considered as a new anatomical structure or a new feature of the existent nucleus.In summary, beside N-d intracellular distribution, there were other three N-d membrane-related localizations: mini-aggregation, patch-aggregation, and arrangement along tubular unit. IntroductionNADPH diaphorase (N-d) is used to a histochemical identification of neuronal cells [1, 2] and also used to detect the neurodegenerative and neuropathological neurites [3][4][5][6][7].Our research interesting is focused on the aging alterations in the lumbosacral spinal cord and dorsal column nuclei. Aging-related neurodegeneration are also detected in the pigeons [8]. The N-d positivity vary with neurons [9] and neuroglia[10] as well as blood vessel endothelium [11, 12]. Morphological feature of neuronal fibers or neurites are definitely distinguishable from neuroglia and blood vessels [11, 13]. The similar observation of the brain and the spinal cord of pigeons are well demonstrated in the anatomical morphology of N-d positivity [8, 14-16]. The gastrointestinal tract of Coturnix coturnix, an avian species is innervated by N-d-ergic neurons, as it is in mammals. Pigeon cloaca, a unique structure for avian is also innervated by N-d-ergic neurons [16]. In general, the N-d positive neurons in the pigeons are similar to the other species[8]. For neuronal cells, N-d histochemistry produces subgroup of positivity based on size of the somata, intensity of enzyme reaction (strong or light intensity), visible processes and less or un-visible process. Many neurons are visible for Golgi-like staining. Some of endothelia of blood vessels are stained with N-d histochemistry. Impression of the N-d staining is superiority to reveal specialized formation, such as aging-related N-d body and megaloneurite in the aged animals[4, 6-8]. However, recently, we found an uncommon N-d positive specialized structures featured with tubul-like components twisted and intermingled formatio...

show abstract

Section: Discussionmentioning

confidence: 99%

Specialized NADPH diaphorase membrane-related localizations in the brainstem of the pigeons (Columba livia)

Jia

Hou

et al. 2019

Preprint

View full text Add to dashboard Cite

show abstract

“…For double ISH/ICC (19), the ICC protocol was incorporated between sample treatment variation in SSC washing and graded alcohol steps of the ISH. Briefly, after washing, the slides were soaked in 1 × PBS pH 7.4 for 10 min and incubated at room temperature for 30 min with 1 × PBS (pH 7.4) containing 1% bovine serum albumin and 0.3% Triton X‐100 to block nonspecific binding.…”

Section: Methodsmentioning

confidence: 99%

Photoperiodic Modulation of Clock Gene Expression in the Avian Premammillary Nucleus

Leclerc

Kang

Mauro

et al. 2010

J Neuroendocrinology

Self Cite

View full text Add to dashboard Cite

The premammillary nucleus (PMM) has been shown to contain a daily endogenous dual-oscillation in dopamine (DA)/melatonin (MEL) as well as c-fos mRNA expression that is associated with the daily photo-inducible phase of gonad growth in turkeys. In the present study, the expression of clock genes (Bmal1, Clock, Cry1, Cry2, Per2 and Per3) in the PMM was determined under short (8 : 16 h light/dark cycle) and long (16 : 8 h light/dark cycle) photoperiods relative to changes associated with the diurnal rhythm of DA and MEL. Constant darkness (0 : 24 h light/dark cycle) was used to assess the endogenous response of clock genes. In addition, light pulses were given at zeitgeber time (ZT) 8, 14 and 20 to ascertain whether clock gene expression is modulated by light pulse stimulation and therefore has a daily phase-related response. In the PMM, the temporal clock gene expression profiles were similar under short and long photoperiods, except that Per3 gene was phase-delayed by approximately 16 h under long photoperiod. In addition, Cry1 and Per3 genes were light-induced at ZT 14, the photosensitive phase for gonad recrudescence, whereas the Clock gene was repressed. Gene expression in established circadian pacemakers, the visual suprachiasmatic nucleus (vSCN) and the pineal, was also determined. Clock genes in the pineal gland were rhythmic under both photoperiods, and were not altered after light pulses at ZT 14, which suggests that pineal clock genes may not be associated with the photosensitive phase and reproductive activities. In the vSCN, clock gene expression was phase-shifted depending on the photoperiod, with apexes at night under short day length and during the day under long day length. Furthermore, light pulses at ZT 14 induced the Per2 gene, whereas it repressed the Bmal1 gene. Taken together, the changes in clock gene expression observed within the PMM were unique compared to the pineal and vSCN, and were induced by long photoperiod and light during the daily photosensitive phase; stimuli that are also documented to promote reproductive activity. These results show that Cry1 and Per3 are involved in the photic response associated with the PMM neuronal activation and are coincident with an essential circadian mechanism (photosensitive phase) controlling the reproductive neuroendocrine system.

show abstract

“…Moreover, in the follow-up confirmation study, low light intensity (10 lux) could not activate PMM in the turkey hypothalamus even in long-day photoperiod (Moore et al, 2018), indicating that light intensity is also a key stimulant of initiation of avian reproductive function as well as photoperiod in avian species. Melanopsin (Opn4) is one of the DBPs which was characterized in the PMM of female turkey (Kang et al, 2007(Kang et al, , 2009(Kang et al, , 2010El Halawani et al, 2009;Leclerc et al, 2010).…”

Section: Effect Of Light On the Behavior And Physiology Of Birdsmentioning

confidence: 99%

Central Nervous System Associated With Light Perception and Physiological Responses of Birds

Kang¹

2021

Front. Physiol.

View full text Add to dashboard Cite

Environmental light that animal receives (i.e., photoperiod and light intensity) has recently been shown that it affects avian central nervous system for the physiological responses to the environment by up or downregulation of dopamine and serotonin activities, and this, in turn, affects the reproductive function and stress-related behavior of birds. In this study, the author speculated on the intriguing possibility that one of the proposed avian deep-brain photoreceptors (DBPs), i.e., melanopsin (Opn4), may play roles in the dual sensory-neurosecretory cells in the hypothalamus, midbrain, and brain stem for the behavior and physiological responses of birds by light. Specifically, the author has shown that the direct light perception of premammillary nucleus dopamine-melatonin (PMM DA-Mel) neurons is associated with the reproductive activation in birds. Although further research is required to establish the functional role of Opn4 in the ventral tegmental area (VTA), dorsal raphe nucleus, and caudal raphe nucleus in the light perception and physiological responses of birds, it is an exciting prospect because the previous results in birds support this hypothesis that Opn4 in the midbrain DA and serotonin neurons may play significant roles on the light-induced welfare of birds.

show abstract

Serotonergic and Catecholaminergic Interactions with Co‐Localised Dopamine‐Melatonin Neurones in the Hypothalamus of the Female Turkey

Cited by 12 publications

References 55 publications

Specialized NADPH diaphorase membrane-related localizations in the brainstem of the pigeons (Columba livia)

Specialized NADPH diaphorase membrane-related localizations in the brainstem of the pigeons (Columba livia)

Photoperiodic Modulation of Clock Gene Expression in the Avian Premammillary Nucleus

Central Nervous System Associated With Light Perception and Physiological Responses of Birds

Contact Info

Product

Resources

About