Serosurvey for assessing PPR vaccination status in rural system of Chhattisgarh state of India

Balamurugan, V.; Muthuchelvan, D.; Govindaraj, G.; Roy, Gautam; Sharma, Varsha; Kumari, Shweta; Choudhary, Dheeraj; Mohanty, Barada Shankar; Suresh, Kuralayanapalya Puttahonnappa; Rajak, Kaushal Kishor; Hemadri, D.; Roy, Parimal

doi:10.1016/j.smallrumres.2018.05.011

Cited by 13 publications

(15 citation statements)

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“…pdf), whereas a cross-sectional stratified random sample serosurvey revealed 55% protection (Balamurugan et al, 2018). Despite higher protection than pre-PPR-MVC level (40%), the threat persists from ingress of disease from other bordering states due to unabated movement of animals across the states for grazing, transit and trade.…”

Section: Discussionmentioning

confidence: 92%

“…In general, the post‐vaccination seroconversion levels provide evidence on the effect of vaccination as well as effectiveness of veterinary service in the area (Gitonga, ). The post‐vaccination seroconversion levels on testing 0.1% of samples was higher (~70%) than OIE‐recommended levels (http://www.fao.org/3/a-i4460e.pdf), whereas a cross‐sectional stratified random sample serosurvey revealed 55% protection (Balamurugan et al., ). Despite higher protection than pre‐PPR‐MVC level (40%), the threat persists from ingress of disease from other bordering states due to unabated movement of animals across the states for grazing, transit and trade.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, Balamurugan et al. () had advocated vaccination till 2019–2020 to attain the desired protection levels in the population. Although it is not advisable on scientific grounds and cost perspective to vaccinate 7–10 years, considering various field problems in developing countries, the extended period of vaccination is necessary to maintain the attained protective immunity levels.…”

Section: Discussionmentioning

confidence: 99%

“…Hence, vaccination on the migratory sheep and goats population at animal movement corridors/check posts/animal markets close to borders of other states and emphasizing vaccination of animals 2-3 weeks prior to entry into the state needed to be implemented strictly to maintain the attained protective immunity levels in the population. Furthermore, Balamurugan et al (2018) had advocated vaccination till 2019-2020 to attain the desired protection levels in the population. Although it is not advisable on scientific grounds and cost perspective to vaccinate 7-10 years, considering various field problems in developing countries, the extended period of vaccination is necessary to maintain the attained protective immunity levels.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of effectiveness of Mass Vaccination Campaign against Peste des petits ruminants in Chhattisgarh state, India

Govindaraj

Roy²,

Mohanty

et al. 2019

Transbound Emerg Dis

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Summary The study evaluated the effectiveness of ‘Mass Vaccination Campaign (MVC)’ implemented against the contagious transboundary OIE notified Peste des petits ruminants (PPR) in sheep and goats on the lines of ‘pulse polio campaign’ for humans in Chhattisgarh state, India. The effectiveness was evaluated on the axes of adequacy, financial viability under with and without MVC through differencing under various scenarios and options and programme impact from a farmer's perspective. The adequacy evaluation revealed that the reported outbreaks, diagnosed and death cases declined under PPR‐MVC inconsonance with increased vaccination coverage. Furthermore, the seroconversion increased during post PPR‐MVC implies elevated immunity levels in the sheep and goat population. The estimated mean mortality loss was USD 45.2 and USD 16.5 per animal in goats and sheep, respectively, whereas the treatment and opportunity cost of labour was USD 1.9 and USD 2.5 per animal respectively. Under the low PPR incidence scenario, benefit: cost ratio, net present value and internal rate of return were 4.9:1, 48.9 million USD and 146.6%, whereas it was 12.4:1,142.7 million USD and 430.4% and 13.5:1,156.7 million USD and 430.4% under medium and high incidence scenarios. Furthermore, the option of vaccinating 100% risk population during the first year followed by 30% during subsequent years to cover naïve population will maximize benefits than 100% coverage every year; nevertheless, benefits outweighs cost manifolds in both of these options. The farmers had a positive opinion on the overall services provided under PPR‐MVC and the results provide the empirical evidence on effectiveness of ‘mass vaccination’ for its replication in other states of India or countries with similar socio‐economic and rearing environments.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Evaluation of effectiveness of Mass Vaccination Campaign against Peste des petits ruminants in Chhattisgarh state, India

Govindaraj

Roy²,

Mohanty

et al. 2019

Transbound Emerg Dis

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“…The working hypothesis of the homogeneous occurrence of PPRV antibodies in the target populations in the epi-units in different states of the study region was considered. Further, the annual growth rate (GR) of PPRV antibodies if mass vaccination continues regularly for the different states was assessed, to predict the number of years of vaccination required to achieve 70% prevalence [ 3 ] using mathematical formula {GR= ([(b−a)/a] × 100)/N} as described earlier [ 8 ], where a-Base level prevalence (30%), b-Study year prevalence, and N-No. of years (3 years).…”

Section: Methodsmentioning

confidence: 99%

Seroprevalence study of peste des petits ruminants in sheep and goats in the northern region of India

et al. 2020

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Background and Aim: Peste des petits ruminants (PPR) is a contagious, World Organization for Animal Health notifiable, economically important, transboundary morbilliviral disease of sheep and goats. Studying seroprevalence of PPR from different geographical areas under varying agro-climatic conditions may help in formulating effective and appropriate disease control strategies under the ongoing national PPR control program. The present cross-sectional study describes the prevalence of PPR virus antibodies in sheep and goats in the various epidemiological units in different states (Haryana, Himachal Pradesh [HP], Jammu and Kashmir [J&K], Punjab, Uttarakhand [UK], and Uttar Pradesh [UP]) of the northern region of India. Materials and Methods: A total of 5843 serum samples (sheep [n=2463] and goats [n=3380]) were collected by stratified random sampling method from 322 epidemiological units in the studied region during 2017-2018 and tested for PPR virus (PPRV) antibodies by competitive ELISA. Results: The results revealed that an overall seroprevalence of 44.05% (2574/5843) with 57.32%, 55.22%, 65.69%, 37.09%, 32.73%, and 29.35% prevalence of PPRV antibodies in small ruminants in Haryana, Punjab, UP, HP, J&K, and UK states, respectively. Further, Chi-squared test revealed an association of PPRV antibodies in goats (χ2=252.28, p<0.01) and sheep (χ2=192.12, p<0.01) across different states in the region. Conclusion: The seroprevalence in majority of the epidemiological units (n=130) in sheep and goats in the studied region had <30%. This necessitates comprehensive, rigorous, continuous vaccination and active surveillance programs for few more years to achieve the desired 70% seroprevalence level of PPRV antibodies in population and to make the northern region of India, as PPR free zone.

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Seroprevalence of peste des petits ruminants in sheep and goats in Eastern India

et al. 2020

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Serosurvey for assessing PPR vaccination status in rural system of Chhattisgarh state of India

Cited by 13 publications

References 13 publications

Evaluation of effectiveness of Mass Vaccination Campaign against Peste des petits ruminants in Chhattisgarh state, India

Evaluation of effectiveness of Mass Vaccination Campaign against Peste des petits ruminants in Chhattisgarh state, India

Seroprevalence study of peste des petits ruminants in sheep and goats in the northern region of India

Seroprevalence of peste des petits ruminants in sheep and goats in Eastern India

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