Seroprevalence survey of Babesia gibsoni infection and tick species in dogs in East China

Cao, Jie; Yang, Qiqing; Zhang, Jianwei; Zhou, Yongzhi; Zhang, Houshuang; Gong, Haiyan; Zhou, Jinlin

doi:10.1016/j.vetpar.2015.10.002

Cited by 23 publications

(25 citation statements)

References 15 publications

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“…B. gibsoni is a virulent protozoan parasite of dogs and is one of the most important tick-borne diseases of domestic dogs. In this study, the ELISA test demonstrated an infection rate for B. gibsoni of 3.91% in pet dogs, which is similar to the seroprevalence reported in pet dogs in East China of 3.47% [ 7 ]. B. gibsoni is transmitted by ticks including H. longicornis [ 31 ] and R. sanguineus [ 32 ].…”

Section: Discussionsupporting

confidence: 86%

“…However, there is very little reliable information on ticks and tick-borne agents in dogs in China. Dominant ticks reported in dogs in China are Rhipicephalus sanguineus , Haemaphysalis longicornis and Rhipicephalus haemaphysaloides [ 7 , 8 ]; the common tick-borne agents found in dogs in China included Ehrlichia canis , Babesia gibsoni, and Anaplasma species [ 7 , 9 , 10 , 11 ]. A survey of the occurrence of Borrelia burgdorferi sensu lato, Ehrlichia canis , and Anaplasma phagocytophilum in dogs was undertaken and found the seroprevalence to be 0.17%, 2.17% and 0.5%, respectively [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

“…A serological investigation of vector-borne diseases in dogs from rural areas of China has shown the seroprevalence of A. phagocytophilum to be 7.7% by the SNAP 4Dx test kit, and 50% by indirect fluorescent antibody (IFA) testing [ 11 ]. A 3.47% seroprevalence of Babesia gibsoni in pet dogs was observed in East China [ 7 ]. Recently, molecular detection has indicated mixed infections with tick-borne Anaplasma species in dogs in Henan, China [ 9 ] and Ehrlichia canis , and Babesia spp.…”

Section: Introductionmentioning

confidence: 99%

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Epidemiological survey of ticks and tick-borne pathogens in pet dogs in south-eastern China

et al. 2017

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To understand the epidemiology of tick infestation and tick-borne diseases in pet dogs in south-eastern China and to develop a reference for their prevention and treatment, we collected 1550 ticks parasitizing 562 dogs in 122 veterinary clinics from 20 cities of south-eastern China. Dogs were tested for common tick-borne pathogens; collected ticks were identified and processed for the detection of tick-borne pathogens. The use of an in vitro ELISA diagnostic kit for antibody detection (SNAP®4Dx® Plus) on dog sera found the infection rates with Borrelia burgdorferi sensu lato, Ehrlichia canis, and Anaplasma spp. to be 0.4%, 1.3% and 2.7%, respectively. By using a specific ELISA method, the infection rate with Babesia gibsoni was 3.9%. Rhipicephalus sanguineus sensu lato, Haemaphysalis longicornis and Rhipicephalus haemaphysaloides were the major tick species identified on pet dogs. PCR tests were conducted to detect five tick-borne pathogens in 617 ticks. The infection rate was 10.2% for E. canis, 3.4% for Anaplasma platys, 2.3% for B. gibsoni, 0.3% for B. burgdorferi s.l. and 0% for Babesia canis. Some ticks were co-infected with two (1.46%) or three pathogens (0.16%). These results indicate the infestation of pet dogs by ticks infected with tick-borne pathogens in south-eastern China, and the need for effective treatment and routine prevention of tick infestations in dogs.

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Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Epidemiological survey of ticks and tick-borne pathogens in pet dogs in south-eastern China

et al. 2017

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“…Studies have revealed that young animals are susceptible to B. canis vogeli infection and their clinical presentations are more severe (Greene, 2011). At present, B. canis vogeli and B. gibsoni have been reported to infect dogs in Jiangxi, Fujian, Anhui, Jiangsu, Chongqing, Guangdong, Guangxi, Hainan, Zhejiang, Shanghai, and Shandong provinces (Shen et al, 1997; Wei et al, 2012; Cao et al, 2015). The transmission vector for B. canis vogeli is Rhipicephalus sanguineus , a tick that is distributed in 15 provinces of China, including Gansu (Teng and Jiang, 1991).…”

Section: Resultsmentioning

confidence: 99%

First Molecular Detection of Piroplasm Infection in Pet Dogs from Gansu, China

et al. 2017

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Babesiosis, the hemolytic disease caused by Babesia, which is a tick-transmitted obligate intraerythrocytic protozoan parasite. This disease is responsible for significant mortality and morbidity rates and enormous economic losses to the livestock industry in tropical and subtropical regions worldwide. In this study, blood samples were collected from 141 pet dogs from Gansu, China, and analyzed for Babesia or Theileria spp. infection using specific PCR and sequencing based on 18S rRNA gene fragments. The results indicated that 18S rRNA gene sequences from 11 samples were similar to the 18S rRNA gene sequences in Babesia canis vogeli (2) and Theileria sinensis (9). The total infected rates of B. canis vogeli and T. sinensis were 1.4% (2/141) and 6.4% (9/141), respectively. This represents the first molecular report of T. sinensis in dogs worldwide and of B. canis vogeli in dogs from Gansu province of China. Furthermore, the finding of T. sinensis in dogs may represent the common infection of this parasite occurring in Gansu.

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“…The south and east regions of China are the most endemic regions for these parasites (Wei et al, 2012 ; Chen et al, 2014 ). In Shanghai, the seroprevalence of B. gibsoni was determined to be 9.23% via indirect ELISA (Cao et al, 2015 ). Yao et al reported that B. gibsoni is the main species responsible for canine babesiosis in Nanjing (Yao et al, 2014 ).…”

Section: Introductionmentioning

confidence: 99%

First Molecular Detection of Babesia gibsoni in Dogs from Wuhan, China

Miao

et al. 2017

Front. Microbiol.

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Canine piroplasmosis is a significant disease in dogs caused by Babesia and Theileria parasites. The clinical manifestations range from mild illness to serious disease depending on the parasite species and the physical condition of the infected dog. Canine piroplasmosis has been reported to be prevalent in China. However, no molecular evidence of the disease has been reported in pet dogs from Wuhan. In this study, 118 blood samples were randomly collected from pet dogs in veterinary clinics. The blood samples were subjected to both microscopic examination and reverse line blot (RLB) hybridization assays to detect piroplasm infection. Parasites were observed in 10 blood samples via microscopic examination, whereas there were 14 Babesia gibsoni-positive RLB tests. Phylogenetic analysis was performed after the 18S rRNA and ITS gene sequences from the 14 positive samples were cloned and sequenced. The results confirmed the existence of B. gibsoni in this area. This is the first molecular report of canine babesiosis in pet dogs from Wuhan, China. Pet dogs are companion animals, and the prevalence of babesiosis will be of concern in daily life. This study will help veterinarians better understand the prevalence of canine babesiosis and provide a guide for disease control in pet dogs.

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Seroprevalence survey of Babesia gibsoni infection and tick species in dogs in East China

Cited by 23 publications

References 15 publications

Epidemiological survey of ticks and tick-borne pathogens in pet dogs in south-eastern China

Epidemiological survey of ticks and tick-borne pathogens in pet dogs in south-eastern China

First Molecular Detection of Piroplasm Infection in Pet Dogs from Gansu, China

First Molecular Detection of Babesia gibsoni in Dogs from Wuhan, China

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