Seroprevalence, Spatial Distribution, and Social Determinants of SARS-CoV-2 in Three Urban Centers of Chile

Vial, Pablo; González, Claudia; Icaza, Gloria; Ramírez-Santana, Muriel; Quezada-Gaete, Rubén; Núñez-Franz, Loreto; Apablaza, Mauricio; Vial, M. Cecilia; Rubilar, Paola; Correa, Juan Carlos Velásquez; Pérez, Claudia; Florea, Andrei; Guzmán, Eugenio; Lavín, María-Estela; Concha, P; Ferrari, Manuel Nájera-De; Aguilera, Ximena

doi:10.2139/ssrn.3933650

Cited by 4 publications

(2 citation statements)

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“…To better understand the risks involved for local staff, and by extension the communities they live in, we analysed whether contagion in this group exceeded expectations (see ESM 3). Because direct comparison of incidence rates was not feasible due to Copa América's compulsory testing programme, we established a baseline for contagion based on seroprevalence studies conducted at the time in Brazil [9,16]. Seroprevalence varied significantly with estimates for 2021 ranging from 17 to 35%, with large variations observed across the country [9,[17][18][19][20][21] (see ESM 4).…”

Section: Findings and Discussionmentioning

confidence: 99%

Safety of International Professional Sports Competitions During the COVID-19 Pandemic: The Association Football Experience

Caniza

Forriol

Pangrazio³

et al. 2022

Sports Med

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Major sporting events were suspended during the most acute phase of the COVID-19 pandemic. Competitions are resuming with enhanced hygiene protocols and altered mechanics. While risks for players and staff have been studied, the impact of large-scale tournaments on the communities that host them remains largely unstudied. CONMEBOL Copa América is one of the first wide-scale international tournaments to be conducted in its original format since the beginning of the COVID-19 pandemic. The tournament saw 10 national teams compete in four Brazilian cities during a period of heightened viral transmission. The analysis of over 28,000 compulsory PCR tests showed that positive cases did not lead to the uncontrolled spread of the disease among staff and players. More importantly, the data indicate that locally hired staff were not exposed to increased risk while working. The Copa América experience shows that international sporting competitions can be conducted safely even under unfavourable epidemiological situations.

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Section: Findings and Discussionmentioning

confidence: 99%

Safety of International Professional Sports Competitions During the COVID-19 Pandemic: The Association Football Experience

Caniza

Forriol

Pangrazio³

et al. 2022

Sports Med

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“…Serum neutralization capacity was measured using a pseudotyped vesicular stomatitis virus with a sequence encoding the enhanced green fluorescent protein as a reporter gene (VSV-GFP-Spike SARS-CoV-2 original Wuhan strain) kindly donated by Dr. Kartik Chandran (6). Samples tested came from individuals enrolled in a population-based SARS-CoV-2 seroprevalence study performed by the same research team (7)(8)(9). In November 2021, we collected 2,198 serum samples from seven-year-old and older people, finding 97.3% of seropositivity.…”

Section: The Studymentioning

confidence: 99%

SARS-CoV-2 neutralizing antibodies in Chile after a vaccination campaign with five different schemes

Aguilera

Hormazábal

Víal

et al. 2022

Preprint

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Assessing the Burden of COVID-19 in Developing Countries: Systematic Review, Meta-Analysis, and Public Policy Implications

Owusu‐Boaitey

Pugh

Fosdick

et al. 2021

Preprint

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Introduction The infection fatality rate (IFR) of COVID-19 has been carefully measured and analyzed in high-income countries, whereas there has been no systematic analysis of age-specific seroprevalence or IFR for developing countries. Indeed, it has been suggested that the death rate in developing countries may be far lower than in high-income countries - an outcome that would be starkly different from the typical pattern for many other infectious diseases. Methods We systematically reviewed the literature to identify all serology studies in developing countries that were conducted using representative samples of specimens collected by early 2021. For each of the antibody assays used in these serology studies, we identified data on assay characteristics, including the extent of seroreversion over time. We analyzed the serology data using a Bayesian model that incorporates conventional sampling uncertainty as well as uncertainties about assay sensitivity and specificity. We then calculated IFRs using individual case reports or aggregated public health updates, including age-specific estimates whenever feasible. Results Seroprevalence in many developing country locations was markedly higher than in high-income countries but still far short of herd immunity. In most locations, seroprevalence among older adults was similar to that of younger age-groups. Age-specific IFRs were 1.3-2.5x higher than in high-income countries. The median value of population IFR was 0.5% among developing countries with satisfactory death reporting as of 2016, compared to a median of 0.05% for other developing countries. Conclusion The burden of COVID-19 is far higher in developing countries than in high-income countries, reflecting a combination of elevated transmission to middle-aged and older adults as well as limited access to adequate healthcare. These results underscore the critical need to accelerate the provision of vaccine doses to vulnerable populations in developing countries.

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Seroprevalence, Spatial Distribution, and Social Determinants of SARS-CoV-2 in Three Urban Centers of Chile

Cited by 4 publications

References 0 publications

Safety of International Professional Sports Competitions During the COVID-19 Pandemic: The Association Football Experience

Safety of International Professional Sports Competitions During the COVID-19 Pandemic: The Association Football Experience

SARS-CoV-2 neutralizing antibodies in Chile after a vaccination campaign with five different schemes

Assessing the Burden of COVID-19 in Developing Countries: Systematic Review, Meta-Analysis, and Public Policy Implications

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