Seroprevalence of Toxoplasma gondii among general population in Bosnia and Herzegovina: 10-Years single center experience

Šušak, Božo; Martinović, Katarina; Jakovac, Sanja; Arapović, Jurica

doi:10.1016/j.cegh.2023.101336

Cited by 2 publications

(2 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, it appears that seroprevalence is higher in older adults, depending on the socioeconomic circumstances of the individuals [80]. Water containing oocysts, drinking unfiltered water, or drinking water in recreational facilities all help spread this illness [81].…”

Section: Epidemiologymentioning

confidence: 99%

A Comprehensive Review of Toxoplasmosis: Serious Threat to Human Health

Khairullah,

Kurniawan,

Widodo

et al. 2024

TOPHJ

View full text Add to dashboard Cite

Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii. Despite infecting a major fraction of the global population, T. gondii rarely results in clinically significant disease. Cats are the only known definitive host for this parasite, which sheds millions of oocysts in its feces every day, which then sporulate and become infective in the environment. This comprehensive review article aims to explain the etiology, pathogenesis, epidemiology, transmission, clinical symptoms, diagnosis, risk factors, public health importance, economic effect, treatment, and prevention of toxoplasmosis. A search for various publications in English with the criteria of reviewing articles explaining toxoplasmosis was carried out. T. gondii reproduces through two life cycles, namely the sexual cycle and the asexual cycle. In general, consuming parasite cysts in tainted food or water is how humans and other warm-blooded animals become infected with T. gondii. Nearly every region of the world has reported incidences of toxoplasmosis in humans, and around one-third of people are susceptible to latent infection. According to the reports, the main ways through which diseases spread are by water, tainted food, eating tissue cysts or oocysts, and congenital transmission. Infected individuals may experience asymptomatic cervical lymphadenopathy during an acute systemic infection. Diagnostic evaluation is very important for early detection, prevention of transmission, and as a reference for treatment options for infected pregnant women. Consuming undercooked meat is traditionally seen as a significant risk factor for developing toxoplasmosis. The impact of toxoplasmosis is very significant in humans because it causes abortion and disease in newborns, resulting in serious economic losses. To treat toxoplasmosis, dihydropteroate synthetase and dihydrofolate reductase inhibitors are advised. Toxoplasma transmission to humans can be avoided by thoroughly washing your hands with soap after handling meat, poultry, or shellfish.

show abstract

Section: Epidemiologymentioning

confidence: 99%

A Comprehensive Review of Toxoplasmosis: Serious Threat to Human Health

Khairullah,

Kurniawan,

Widodo

et al. 2024

TOPHJ

View full text Add to dashboard Cite

show abstract

“…Each region also had considerable heterogeneity among countries [4]. Notably, there has been a consistent downward trend in toxoplasmosis prevalence across Europe over the past few decades, including the Balkan countries, and among them Serbia [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Factors Associated with Toxoplasma gondii Seroprevalence in Pregnant Women: A Cross-Sectional Study in Belgrade, Serbia

Marković-Denić,

Stopić,

Bobić

et al. 2023

Pathogens

View full text Add to dashboard Cite

Toxoplasmosis, caused by the cosmopolitan protozoan Toxoplasma gondii, has particular implications during pregnancy due to the possible transmission of infection to the fetus. Very few studies have assessed seroprevalence and the risk factors for toxoplasmosis in healthy pregnant women. The aim of this study was to examine the seroprevalence of T. gondii infection in healthy pregnant women and to identify the associated risk factors for toxoplasmosis. The cross-sectional study involved 300 healthy pregnant women who came to the Institute for Blood Transfusion in Belgrade between November 2018 and February 2019 for routine blood group and Rh factor testing before delivery, who were also tested using serological screening for the presence of specific antibodies. Positives were further examined using enzyme immunoassay. Of the total sera of participants analyzed, 38 were positive for specific IgG, resulting in a seroprevalence rate of 12.7% (95% Confidence Interval (CI) 9.1–17.0%). All pregnant women presented negative anti-T. gondii IgM antibodies. The multivariate logistic regression analysis revealed that living in a house with a garden was independently associated with the risk of T. gondii infections, while eating chicken meat was connected with a lower risk compared to eating other types of meat with an odds ratio (OR) of 2.5 (95% CI 1.21–5.02) and an OR of 0.3 (95% CI 0.09–0.83), respectively. Although the prevalence of anti-T. gondii IgG antibodies is relatively low, it is essential to maintain and adapt evidence-based preventive measures for toxoplasmosis continually.

show abstract

Seroprevalence of Toxoplasma gondii among general population in Bosnia and Herzegovina: 10-Years single center experience

Cited by 2 publications

References 26 publications

A Comprehensive Review of Toxoplasmosis: Serious Threat to Human Health

A Comprehensive Review of Toxoplasmosis: Serious Threat to Human Health

Factors Associated with Toxoplasma gondii Seroprevalence in Pregnant Women: A Cross-Sectional Study in Belgrade, Serbia

Contact Info

Product

Resources

About