Seroprevalence of Rubella in northeastern Turkey

Akkoyunlu, Yasemin; Arvas, Gülhan; Özsarı, Tamer; Hakyemez, İsmail Necati; Kaya, Bülent; Aslan, Turan

doi:10.1007/s00508-013-0378-3

Cited by 4 publications

(3 citation statements)

References 6 publications

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“…Also effectiveness of rubella mass vaccination it has also proven in other countries. [16][17][18] The increased trend of anti-rubella antibody with aging was shown in this study, which is maybe due to higher risk of disease or contact with virus with increase in age. Although this trend was not significant which could be due to the fact that the sample size of present study did not have enough power to show changes in trend.…”

Section: Discussionmentioning

confidence: 55%

Sero-epidemiological evaluation of rubella immunity among pre-marriage women in Iran

Zahraei

Mokhtari‐Azad

Sabouri

et al. 2019

Human Vaccines & Immunotherapeutics

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Few studies have addressed the seroepidemiological profile of rubella among a representative population of young adult women. This study aims to determine the immunity and susceptibility rate against rubella in a representative population of women in reproductive age in Iran through serological evaluation. This cross-sectional study was conducted in 2012 on 804 pre-marriage women in Iran. Multi-stage random sampling was used for choosing study sample. Serologic test were used to assess subjects' immunity to rubella and their titers of IgG antibody against rubella with Elisa method was measured. In total, 98.4% (95% CI: 97.1% -97.3%) of study participants were immune against rubella. Five women (0.6%) were in borderline category and 1% (8 women) was susceptible to rubella. The proportion of immune people in low and high incidence regions was 99.3% (95% CI: 97.8-99.9%), and 97.5% (95% CI: 95.5-95.89%), respectively (P = 0.05). Our data indicated that level of immunity to rubella in women of reproductive age in Iran is satisfactory. This finding indicates the achievement of Iran to the goal of high level of serum immunity against rubella among young women.

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Section: Discussionmentioning

confidence: 55%

Sero-epidemiological evaluation of rubella immunity among pre-marriage women in Iran

Zahraei

Mokhtari‐Azad

Sabouri

et al. 2019

Human Vaccines & Immunotherapeutics

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“…Similar findings were reported in Sweden, with a seroprevalence of 95.8% among 41637 individuals after 22 years of an MMR immunization program (10). Akkoyunlu et al in northeastern Turkey revealed 73% (11) and Calimeri et al in Italy measured 85.8% (12) immunity in their studies. According to the cost-effectiveness analysis performed, systematic vaccination costs three to four times less than elective vaccination (13).…”

Section: Discussionmentioning

confidence: 82%

Rubella Immunity in Women of Childbearing Age, Eight Years After the Immunization Program in Iran

Sawadkohi¹,

Zarghami²,

Izadpana³

et al. 2014

Iran Red Crescent Med J

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Background:Rubella is a viral disease with a worldwide distribution. Mass vaccination campaigns have increased the vaccine coverage in the world with substantial impact on reduction of rubella infections. In Iran, the national measles-rubella campaign, targeting individuals 5-25 years old, was initiated in 2003 and mass childhood vaccination against measles, rubella and mumps has continued ever since.Objectives:The aim of this study was to evaluate the efficacy of routine vaccination on rubella immunity among women of childbearing age in Babol, north of Iran.Patients and Methods:This cross-sectional study was conducted on 812 women of childbearing age living in Babol, north of Iran, in 2011. Twelve samples were excluded from the study because of inadequate sera amounts. Serum samples were examined for presence of rubella-specific IgG antibodies by means of quantitative ELISA.Results:From a total of 800 samples in this study, rubella IgG seropositivity was seen in 786 (98.3% [95% CI = %97.5-%99.1]) cases. The maximum IgG seropositivity (99.2%) was seen in the age group of 21-25 years old and the lowest immunity (87.7%) was in the group of above 30 years old.Conclusions:Our data indicated that the rate of seropositivity to rubella virus in our population was high, suggesting that vaccination has been successful in Babol, reducing the likelihood of congenital rubella infection.

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“…In a study in Brazil, positive antibody titer was reported as 76% ( 23 ). Other studies in Turkey ( 24 ), India ( 25 ), Syria ( 26 ), Sudan ( 27 ) and Burkina-Faso ( 28 ) reported anti-rubella antibody titers as 81.8%, 87.2%, 85.6%, 95.1% and 95%, respectively. In Iran, several studies were conducted in different age groups before national vaccination in 2003 and reported immunity of women of reproductive age as 78%-94% ( 29 - 32 ), which showed high susceptibility of this age group to rubella and potential CRS in infants born of these women.…”

Section: Discussionmentioning

confidence: 95%

Seroepidemiology of Rubella in Women Under 25 Years Old Attending Medical Centers in Ahvaz, Iran in 2013

Boroujerdnia¹,

Shakunia

Alavi

et al. 2015

Jundishapur J Microbiol

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Background:Rubella is a mild viral infection affecting women of reproductive age, and the fetus in early pregnancy, leading to miscarriage, stillbirth and Congenital Rubella Syndrome.Objectives:The present study aimed to assess serum level of anti-rubella antibodies in women younger than 25 years attending medical centers in Ahvaz city.Patients and Methods:This descriptive cross-sectional study was conducted on 760 women younger than 25 years attending medical centers in Ahvaz. A sample of 3 mL of venous blood was taken from each woman and ELISA method was used to assess anti-rubella IgG levels. Antibody level more than 11 IU/mL was considered safe. Data was analyzed by SPSS software using Chi-square, ANOVA and Pearson Correlation tests.Results:Of total samples, 683 women (88.9%) had immunity against rubella, 80 (10.4%) no immunity and 5 (0.7%) intermediate levels of antibody. Immunity to rubella increased significantly with aging (P = 0.001) and a significant association was found between age and antibody titer (P = 0.001, r = 0.261).Conclusions:More than 95% of 15 to 25 year-old women (main reproductive age in Iran) are within acceptable immunity range. Level of immunity to rubella in women of reproductive age in this region appears satisfactory.

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Seroprevalence of Rubella in northeastern Turkey

Abstract: In spite of the active immunization programme commenced after 2006, rubella infection is still a risk in Turkey without discriminating the gender.

Cited by 4 publications

References 6 publications

Sero-epidemiological evaluation of rubella immunity among pre-marriage women in Iran

Sero-epidemiological evaluation of rubella immunity among pre-marriage women in Iran

Rubella Immunity in Women of Childbearing Age, Eight Years After the Immunization Program in Iran

Seroepidemiology of Rubella in Women Under 25 Years Old Attending Medical Centers in Ahvaz, Iran in 2013

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