Seroprevalence of Newcastle Disease Virus (NDV) in Commercial and Domesticated Birds: during Current Surge of NDV in Pakistan Read more at http://nexusacademicpublishers.com/table_contents_detail/2/780/html#XReXlURQzEU7Fqej.99

Ul-Rahman, Aziz; Habib, Momena; Riaz, Tayyaba; Hussain, Behzad; Yousaf, Farooq; Saqalein, Muhammad; Rasool, Muhammad Hidayat

doi:10.14737/journal.jimb/2016/4.4.54.59

Cited by 4 publications

(1 citation statement)

References 11 publications

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“…However, the largest endemic regions are the African and Asian subcontinents, which include China, India, Pakistan, Malaysia, and Bangladesh (Abdisa and Tagesu, 2017). Pakistan has a prevalence of ND of about 82.3% (Aziz-ul-Rahman et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

The Comparative Effect of Herbal and Allopathic Immune Stimulators on the Efficacy of Newcastle Disease Vaccine in Broiler

Ara,

Saleem,

Chaudry

et al. 2023

PJS

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The modulation of the broiler immune system by using immune-stimulating compounds provides a promising solution and it enhances the immune response to a broad range of viral and bacterial infections without causing any risk. The current in-vitro study included 18-day-old broiler chicks (Ross-308) divided into three equal groups i.e. A, B, and C comprising 6 birds each. The study was conducted to investigate the comparative efficacy of ND vaccine at days 5 and 18 orally in combination with two commercially available immune stimulators i.e. Powder Lisovit® (A blend of growth stimulators, carbohydrates, and vitamins manufactured by Biomin, Austria) administered @ 1gm/ 4 lit of drinking water twice a week for 5 weeks in group A and Liquid Virnet® (A blend of immune boosting and growth-enhancing natural herbs manufactured by Seza Pharma, Pakistan) administered @ 1ml/ lit of drinking water twice a week for 5 weeks in group B, while group C was attributed as control group and only ND vaccine was given with the same regime as in A and B. The blood sampling of all groups was done at days 0, 10, 20, and 35 for antibody titers estimation through a haem-agglutination inhibition test. The feed conversion ratio (FCR) was also calculated weekly. The mean values of antibody titers of group A and B individually were found highly significant (P=0.001) as compared to group C while the mean values of antibody titers of group A and B were non-significant (P=0.35) with each other. Similarly, the mean values of the weekly FCR of groups A and B were not significantly different (P=0.27) from each other, while the mean values of the weekly FCR of groups A and B individually were highly significant (P=0.001) as compared to the group C. The immune stimulators under study showed a significant effect on growth performance and an additive effect on ND vaccine titers. In the light of study results, it may be strongly recommended to use the immune stimulators as a routine practice to mitigate the deadly poultry diseases like ND.

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Section: Introductionmentioning

confidence: 99%

The Comparative Effect of Herbal and Allopathic Immune Stimulators on the Efficacy of Newcastle Disease Vaccine in Broiler

Ara,

Saleem,

Chaudry

et al. 2023

PJS

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A comparative genomic and evolutionary analysis of circulating strains of Avian avulavirus 1 in Pakistan

2019

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Newcastle disease, caused by Avian avulavirus 1 (AAvV 1), is endemic to many developing countries around the globe including Pakistan. Frequent epidemics are not uncommon even in vaccinated populations and are largely attributed to the genetic divergence of prevailing isolates and their transmission in the environment. With the strengthening of laboratory capabilities in Pakistan, a number of genetically diverse AAvV 1 strains have recently been isolated and individually characterized in comparison with isolates reported elsewhere in the world. However, there lacks sufficient comparative genomic and phylogenomic analyses of field circulating strains that can elucidate the evolutionary dynamics over a period of time. Herein, we enriched the whole genome sequences of AAvV reported so far (n= 35) from Pakistan and performed comparative genomic, phylogenetic and evolutionary analyses. Based on these analyses, we found only isolates belonging to genotypes VI, VII and XIII of AAvV 1 in a wide range of avian and human hosts. Comparative phylogeny revealed the concurrent circulation of avualviruses representing different sub-genotypes such as VIg, VIm, VIIa, VIIb, VIIe, VIIf, VIIi, XIIIb and XIIId. We found that that isolates of genotype VII were more closely associated with viruses of genotype XIII than genotype VI. An inter-genotype comparative residue analysis revealed a few substitutions in structurally and functionally important motifs. Putative recombination events were reported for only one of the captive-wild bird (pheasant)origin isolates. The viruses of genotype VII had high genetic diversity as compared to isolates from genotypes VI and XIII and, therefore, have more potential to evolve over time. Taken together, the current study provides an insight into the genetic diversity and evolutionary dynamics of AAvV 1 circulating in Pakistan. Such findings are expected to facilitate better intervention strategies for the prevention and control of ND in disease-endemic countries across the globe particularly Pakistan.

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Determinants of Newcastle disease in commercial layer chicken farms in two districts of Bangladesh: A case-control study

Roky

Das

Akter

et al. 2022

Heliyon

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Seroprevalence of Newcastle Disease Virus (NDV) in Commercial and Domesticated Birds: during Current Surge of NDV in Pakistan Read more at http://nexusacademicpublishers.com/table_contents_detail/2/780/html#XReXlURQzEU7Fqej.99

Cited by 4 publications

References 11 publications

The Comparative Effect of Herbal and Allopathic Immune Stimulators on the Efficacy of Newcastle Disease Vaccine in Broiler

The Comparative Effect of Herbal and Allopathic Immune Stimulators on the Efficacy of Newcastle Disease Vaccine in Broiler

A comparative genomic and evolutionary analysis of circulating strains of Avian avulavirus 1 in Pakistan

Determinants of Newcastle disease in commercial layer chicken farms in two districts of Bangladesh: A case-control study

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