Seroprevalence of mumps before inclusion of mumps vaccination in the Iranian Expanded Programme on Immunization

Abstract

The current target groups for measles, mumps and rubella vaccination in the Islamic Republic of Iran are children at 12 months and 4-6 years. A study of the age-specific seroprevalence of antibodies against mumps in children aged 3-18 years in Shahrekord aimed to establish the need for booster vaccinations to cover non-immune children. Of 338 children, 19.8% were seronegative. Age-specific seronegativity was 33.3%, 20.5% and 4.6% in age groups 7-11, 12-14 and 15-18 years respectively. To obtain herd immunity, we suggest that for the next 5 years children aged 7-11 years entering guidance school are selected as the main group for vaccination. Séroprévalence des oreillons avant l'intégration de la vaccination anti-ourlienne dans le programme élargi de vaccination iranien RÉSUMÉ À l'heure actuelle, les groupes visés par la vaccination contre la rougeole, les oreillons et la rubéole en République islamique d'Iran sont les enfants âgés de 12 mois et ceux âgés de 4 à 6 ans. Une étude de la séroprévalence par âge des oreillons chez les enfants âgés de 3 à 18 ans a été menée à Shahrekord, dans le but de déterminer s'il y avait lieu de procéder à des vaccinations de rappel afin de protéger les enfants non immunisés. Sur 338 enfants, 19,8 % étaient séronégatifs. La séronégativité selon le critère de l'âge était respectivement de 33,3 %, 20,5 % et 4,6 % dans les groupes de sujets âgés de 7 à 11 ans, de 12 à 14 ans et de 15 à 18 ans. Pour obtenir une immunité collective, nous suggérons que pendant les 5 prochaines années, le principal groupe vacciné soit les enfants âgés de 7 à 11 ans, avant leur entrée dans le second degré. Seroprevalence of mumps ‫للتمنيع‬ ‫ع‬

High Proportion of School Aged Children Susceptible to Mumps Virus Infections in the City of Mwanza, Tanzania: Should It be Included in the National Immunization Programme?

“…In comparison to a previous study in South Africa which reported 9% of children with meningitis to have mumps virus, the reported seropositivity in this current study is indeed high [20]. When compared to previous studies in other countries outside Africa; the reported seropositivity in the current study is low compared to 80.2%, 71.9%, 89.1, 71.1 and 69.4% reported in Iran, Yemen, Ankara Turkey, Eastern Turkey and Brazil, respectively [1,18,24,29,30]. The possible explanation for these variations could be due to differences in seasonality, study populations, geographical and climatic conditions.…”

The High Seropositivity of Mumps Virus IgG Antibodies among School-Aged Children in Rural Areas of the Mbarali District in the Mbeya Region, Tanzania: It Is High Time for Consideration in the National Immunization Program

“…In addition, the two studies used the same assays, making the data more comparable. In comparison to previous reports elsewhere, the seropositivity reported in the current study is also comparable to 91.6% in Colombia, 89.1% in Yemen, 80.2% in Iran, 71.9% in Turkey, and 69.4% in Brazil [13,[24][25][26][27][28][29]. However, in comparison to a previous report in Mwanza that reported a seropositivity of 21.4%, the seropositivity reported in the current study is indeed high [21].…”

A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents

“…One thousand two hundred seventeen samples before the nationwide immunization campaign and 2007 after running the program were collected from 10 provinces of Iran and were tested for IgG antibody rubella. The antibodies increased from 73.4% before the operation to 98.8% after the vaccination ( 22 – 23 ).…”

“…Demographic data [including age, sex, area of residence (rural/urban), an education level (elementary/intermediate), Body mass index (BMI) and province] of the selected samples were extracted from CASPIAN-V database. Iran was divided into four main regions; north-northeast, central, west, and southeast based on geographical and socioeconomic state of the provinces, according to a previous study ( 22 ). BMI z-score was calculated based on the World Health Organization (WHO) growth references for each sex and age ( 23 ).…”