Seroprevalence of Human Immunodeficiency Virus (HIV) among Blood Donors Attending National Blood Transfusion and Research Center in Sana'a City, Yemen: Warning Sign

Alzubiery, Tawfique KA; Alsumairy, Hafez; Alharazi, Talal; AL-Zubeiry, A. H. S.; Jabir, Amar A.; saleh, Majedi A.; Muckbil, Manal Jamil

doi:10.9734/isrr/2018/39984

Cited by 3 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The present study revealed a lower prevalence (0.2%) of anti-HIV Ab than previous studies conducted in Sana’a city, with a prevalence of 0.3 to 0.6% [ 19 , 20 ]. A recent study illustrated an approximate similarity in the prevalence of anti-HIV [ 39 ].…”

Section: Discussioncontrasting

confidence: 84%

“…The current study revealed a higher prevalence (2.0%) of anti-HCV antibodies compared to studies conducted in the same area (Sana'a) (1.0% and 1.6%) [16,19]. However, this study has a lower prevalence than the studies of Alodini (3.0%) [35] and Saghir et al…”

Section: Hcvcontrasting

confidence: 69%

“…However, this is still far from the global target of fewer than 500,000 new infections by the year 2020 [ 6 ]. In Yemen, it was reported that the prevalence of HIV ranges from 0.30% to 0.60% [ 13 , 19 ], and syphilis from 0.60% to 0.75% with the number of cases expected to increase [ 20 ]. In addition, 17.1 million people aged 15–49 are expected to be infected with T. pallidum annually [ 6 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence of Transfusion-Transmitted Infections (HCV, HIV, Syphilis and Malaria) in Blood Donors: A Large-Scale Cross-Sectional Study

et al. 2022

Self Cite

View full text Add to dashboard Cite

Blood plays a major role in transmitting infectious diseases such as hepatitis C virus (HCV), human immunodeficiency virus (HIV), hepatitis B virus (HBV), syphilis, malaria, and many others. Thus, this study sought to evaluate the distribution of HCV, HIV, syphilis, and malaria among blood donors in Yemen. This is a cross-sectional study, conducted on blood donors at the national center in Yemen. Blood donors’ specimens were serologically tested for the presence of anti-HCV and anti-HIV antibodies, as well as anti-Treponema pallidum, anti-Plasmodium falciparum, and anti-Plasmodium vivax. A total of 16,367 donors were included in this study. Based on the donor’s occupation, the study showed that the relative seroprevalence of anti-HCV Ab among the donors was statistically significant, and relatively high prevalence was found among military donors (2.8%). Positive HIV antibody tests were only reported in 33 male donors (0.2%), who were mostly manual workers. A remarkably high prevalence of anti-Treponema pallidum was observed among manual workers (3.1%). There was a statistically significant difference in the distribution of anti-malaria Ab based on residency and age groups. This study revealed that the prevalence of HCV, HIV, syphilis, and malaria among donors was 2.0%, 0.2%, 2.4%, and 0.7%, respectively. Further genotyping studies are necessary to provide a complete picture of the prevalence of transfusion-transmitted infections (TTIs).

show abstract

Section: Discussioncontrasting

confidence: 84%

Section: Hcvcontrasting

confidence: 69%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of Transfusion-Transmitted Infections (HCV, HIV, Syphilis and Malaria) in Blood Donors: A Large-Scale Cross-Sectional Study

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

“…This could be accounted for by the improvement in transfusion safety strategies at the level of the pre-donation phase because the selection of donors is done rigorously, failing any donation participant who does not meet the selection criteria (no sex between men, no sex with multiple partners, no sex for money, no change of sex partners in the last 3 months, no chronic infections, no drug use injectables.. ) established by the NBTC.This seroprevalence was similar to that of studies carried out in some developing countries such as Ethiopia (1.4%), Uganda (1.03%), Yemen (0.6%), Eritrea. (0.8%) Nigeria (1.1%), Kenya (1.15%) and South Africa (1.13%) [9][10][11][12][13][14][15]. This slight difference in seroprevalence could be due to the behavioral characteristics of study participants, geographic distribution, different procedures for selecting participants for donation, and screening strategy that differs from country to country.…”

Section: Discussionmentioning

confidence: 99%

“…This explanation could be due to the sexual practice for money which would lead them to adopt risky sexual behaviors (multiplicity of sexual partners). Some studies in Ethiopia and Mali showed that women were 1.6 times more at risk (OR = 1.6) than men and the 25-34 age group was also at risk compared to other age groups [7][8][9][10][11][12][13][14][15][16]. And concerning the profession of the donor, it emerged that students/pupils and the unemployed had high seropositivity (0.8% and 1.0% respectively).…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence and Risk Factors Associated with Human Immunodeficiency Virus Infection Type 1 in Donors of the National Blood Transfusion Center of Libreville (Gabon)

Mangala

Nkoa

Maulot-Bangola

et al. 2021

I-SRR

View full text Add to dashboard Cite

Background: Transmission of HIV through blood transfusion remains a public health problem, particularly in countries in Sub-Saharan Africa. However, no study has determined the epidemiological data regarding HIV-1 infection in Gabonese blood donors. The objective of this study is to assess the seroprevalence of HIV-1 and the risk factors associated with infection in donors from the National Blood Transfusion Center in Libreville (Gabon). Methods: A cross-sectional study carried out from June to August 2020 in 3669 persons donating blood at the National Blood Transfusion Center (NBTC). The ELISA technique (Evolis®, BioRad), the chemiluminescence technique (Cobas® e601, Roche), and the SD Bioline® HIV 1/2 test (Standard Diagnostics. Inc) were used for the detection of anti-HIV-1/2 antibodies and P24 antigen in donor plasma. Data were analyzed using SPSS software version 21.0, with p˂.05 considered statistically significant. Results: The seropositivity rate HIV-1 was 0.8% (30/3669) (95% CI: 0.5; 1.1). The study was composed of 79.4% men and 20.6% women. The most representative age group was of 25-34 years with 54.5%. The seropositivity of men, women, and unrelated voluntary donors was 0.7%, 1.2%, and 1.0%, respectively. The risk factors such as the first blood donation (Adjusted Odds Ratio (AOR) = 0.1 [0.0 ;0.4], P= .002), multiple sexual partners (AOR = 6.2 [2.2;17.2], P= .001), primary educational level (AOR = 10.1 [1.4;75], P = .024), and dental care (AOR = 3.6 [1.2;11], P = .024) were significantly associated with HIV infection. About 0.14% of the patients had co-infection. Conclusion: In the Gabonese context, about one out of a hundred blood donors are HIV-infected. These carriers of HIV infection in the blood banks are mainly new donors with multiple sexual partners, limited education, and poor dental care.

show abstract

COVID-19 impact on blood donor characteristics and seroprevalence of transfusion-transmitted infections in southern Thailand between 2018 and 2022

Burananayok,

Nachatri,

Choothanorm

et al. 2024

Sci Rep

View full text Add to dashboard Cite

Blood safety is a critical aspect of healthcare systems worldwide involving rigorous screening, testing, and processing protocols to minimize the risk of transfusion-transmitted infections (TTIs). The present study offers a comprehensive assessment of the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and syphilis among blood donors in southern Thailand. It explores the consequences of the COVID-19 pandemic on the blood transfusion service, donor characteristics, and the prevalence of TTIs. A retrospective analysis of 65,511 blood donors between 2018 and 2022 was conducted at Songklanagarind Hospital, Thailand. The socio-demographic characteristics of the donors were examined using the Chi-square test to assess the relationship between TTIs serological positivity and donor characteristics. The donors were divided into pre-COVID-19 (2018–2019) and during COVID-19 (2020–2022) groups to evaluate the impacts of COVID-19. The study found that HBV had the highest overall prevalence at 243 per hundred thousand (pht), followed by syphilis (118 pht), HCV (32 pht), and HIV (31 pht) over a five-year period of study. After COVID-19, the prevalence of HBV decreased by 21.8%; HCV decreased by 2.1%; HIV increased by 36.4%; and syphilis increased by 9.2%. The socio-demographic characteristics and TTIs prevalence were significantly altered over time. This study provides insights into blood donor characteristics and TTIs prevalence in southern Thailand, highlighting the understanding of the impact of COVID-19 on the spread of TTIs.

show abstract

Seroprevalence of Human Immunodeficiency Virus (HIV) among Blood Donors Attending National Blood Transfusion and Research Center in Sana'a City, Yemen: Warning Sign

Cited by 3 publications

References 0 publications

Prevalence of Transfusion-Transmitted Infections (HCV, HIV, Syphilis and Malaria) in Blood Donors: A Large-Scale Cross-Sectional Study

Prevalence of Transfusion-Transmitted Infections (HCV, HIV, Syphilis and Malaria) in Blood Donors: A Large-Scale Cross-Sectional Study

Seroprevalence and Risk Factors Associated with Human Immunodeficiency Virus Infection Type 1 in Donors of the National Blood Transfusion Center of Libreville (Gabon)

COVID-19 impact on blood donor characteristics and seroprevalence of transfusion-transmitted infections in southern Thailand between 2018 and 2022

Contact Info

Product

Resources

About