Seroprevalence of hepatitis E virus (HEV) among male craft and manual workers in Qatar (2020–2021)

Younes, Nadin; Yassine, Hadi M.; Nizamuddin, Parveen Banu; Kourentzi, Katerina; Tang, Patrick; Ayoub, Houssein H.; Khalili, Makiyeh; Coyle, Peter V.; Litvinov, Dmitri; Willson, Richard C.; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.

doi:10.1016/j.heliyon.2023.e21404

Cited by 2 publications

(1 citation statement)

References 42 publications

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“…This study tested deidentified stored blood serum specimens collected during a nationwide serological survey conducted from July 26, 2020, to September 09, 2020 to determine the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence among CMWs (14,18,19). The survey's sampling strategy was formulated following an analysis of the registered users' database of the Qatar Red Crescent Society (QRCS), the primary healthcare provider for CMWs in the country (14).…”

Section: Study Design Sampling and Specimen Collection And Handlingmentioning

confidence: 99%

Prevalence of hepatitis A virus among migrant workers in Qatar: A national study

Younes,

Chemaitelly,

Nizamuddin

et al. 2024

Preprint

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Background Hepatitis A virus (HAV) is the predominant cause of acute viral hepatitis worldwide; however, data on HAV antibody prevalence (seroprevalence) among migrant populations are limited. This study aimed to investigate HAV seroprevalence among Qatar's migrant craft and manual workers (CMWs), constituting approximately 60% of the country's population. Methods HAV antibody testing was conducted on stored serum specimens obtained from CMWs during a nationwide severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) population-based cross-sectional survey between July 26 and September 9, 2020. Associations with HAV infection were investigated through regression analyses. Results Of the 2,607 specimens with HAV antibody test results, 2,393 were positive, and 214 were negative. The estimated HAV seroprevalence among CMWs was 92.0% (95% CI: 90.9-93.1%). HAV seroprevalence was generally high but exhibited some variation, ranging from 70.9% (95% CI: 62.4-78.2%) among Sri Lankans to 99.8% (95% CI: 98.2-99.9%) among Pakistanis. The multivariable regression analysis identified age, nationality, and educational attainment as statistically significant factors associated with HAV infection. Relative to CMWs aged ≤29 years, the adjusted relative risk (ARR) was 1.06 (95% CI: 1.03-1.10) in CMWs aged 30-39 years and reached 1.15 (95% CI: 1.10-1.19) in those aged ≥50 years. In comparison to Indians, the ARR was lower among Sri Lankans, assessed at 0.81 (95% CI: 0.72-0.91), but higher among Nepalese at 1.07 (95% CI: 1.04-1.11), Bangladeshis at 1.10 (95% CI: 1.07-1.13), Pakistanis at 1.12 (95% CI: 1.09-1.15), and Egyptians at 1.15 (95% CI: 1.08-1.23). No evidence for differences was found by geographic location or occupation. Conclusions HAV seroprevalence among Qatar's CMW population is very high, with over nine out of every ten individuals having been exposed to this infection, likely during childhood.

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Section: Study Design Sampling and Specimen Collection And Handlingmentioning

confidence: 99%

Prevalence of hepatitis A virus among migrant workers in Qatar: A national study

Younes,

Chemaitelly,

Nizamuddin

et al. 2024

Preprint

Self Cite

View full text Add to dashboard Cite

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Prevalence of hepatitis B and C viruses among migrant workers in Qatar

Nasrallah,

Chemaitelly,

Ismail

et al. 2024

Sci Rep

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Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft and manual workers (CMWs), constituting 60% of the country's population. Sera collected during a nationwide COVID-19 population-based cross-sectional survey on CMWs between July 26 and September 9, 2020, underwent testing for HBsAg and HCV antibodies. Reactive samples underwent confirmatory testing, and logistic regression analyses were employed to explore associations with HBV and HCV infections. Among 2528 specimens tested for HBV infection, 15 were reactive, with 8 subsequently confirmed positive. Three samples lacked sufficient sera for confirmatory testing but were included in the analysis through multiple imputations. Prevalence of current HBV infection was 0.4% (95% CI 0.2–0.7%). Educational attainment and occupation were significantly associated with current HBV infection. For HCV infection, out of 2607 specimens tested, 46 were reactive, and 23 were subsequently confirmed positive. Prevalence of lifetime HCV infection was 0.8% (95% CI 0.5–1.2%). Egyptians exhibited the highest prevalence at 6.5% (95% CI 3.1–13.1%), followed by Pakistanis at 3.1% (95% CI 1.1–8.0%). Nationality, geographic location, and occupation were significantly associated with lifetime HCV infection. HBV infection is relatively low among CMWs, while HCV infection falls within the intermediate range, both compared to global and regional levels.

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Seroprevalence of hepatitis E virus (HEV) among male craft and manual workers in Qatar (2020–2021)

Cited by 2 publications

References 42 publications

Prevalence of hepatitis A virus among migrant workers in Qatar: A national study

Prevalence of hepatitis A virus among migrant workers in Qatar: A national study

Prevalence of hepatitis B and C viruses among migrant workers in Qatar

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