Seroprevalence of hepatitis C virus among patients at a tertiary health care centre in Rajasthan, India

Mathur, Abhinav; Goyal, Laxmi Kant; Sharma, Manoj Kumar; Gupta, Arvind; Hooja, Nupur; Yadav, R. N.

doi:10.18203/2349-3933.ijam20201123

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…The prevalence of hepatitis C and B infections has been reported to be 6.7% 18 and 2.5%, respectively in the general population of Pakistan 19,20 . The results of our study present a much lower prevalence of hepatitis B and C as compared to the study carried out at Nawabshah city of Sindh Province, Pakistan conducted by Samo et al with the prevalence of hepatitis C at 14.3% and hepatitis B virus as 6.7% 21,22 .…”

Section: Discussionmentioning

confidence: 99%

A Large Data Set; Hepatitis B and C Infection in Pregnant Females

Zafar¹,

Javed²,

Naveed³

et al. 2022

PJMHS

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Background: Hepatitis B and C virus (HBV & HCV) infection is on the surge among pregnant women as a result of unsaved dental and cosmetic procedures, reuse of needles, raising the risk of perinatal transmission and HBV & HCV infection in children. Although few studies on the prevalence of HBV and HCV infection during pregnancy have been conducted but the majority of the studies are on very low sample size. The current study is based on large data set. Objectives: The major goal of this study was to find out the frequency of HBV & HCV in pregnant women. Methods: We conducted a retrospective cohort study in Alkhidmat Raazi Hospital Rawalpindi. A total of 31911 pregnant women who delivered between 2016 and 2021 were analyzed and categorized as HBV & HCV infected or HBV & HCV uninfected by billing codes. The birth certificate and hospital discharge records were used to identify infant records related to HBV and HCV-infected pregnant mothers. Pregnant women's plasma samples were tested for HBV and HCV using chemiluminescence ARCHITECT i1000SR® Abbott Diagnostics. Data were analyzed using packages within SPSS software and P ≤ 0.05 was considered significant. Cross-tabulation chi-square analysis was performed with a significance level of 5%. Results: The pregnant women with age under 25 years were 12699 (39.8%), women with age from 26 to 29 years were 9734 (30.5%), while women with age 30 and older were 9478 (29.7). The patients who were primigravida were 9514 (29.8%), multipara having 1-4 children 18545 (58.1%) and those having more than five children were 3852 (12.1%). The prevalence of HBV and HCV in 31911 pregnant women were 170/31911 (0.5%) and 478/31911 (1.5%), respectively. The mean age was 27.9 years. Conclusions: HBV and HCV infection is present in pregnant females, which may ultimately increase the treatment cost and vertical transmission. Keywords: Hepatitis B, Hepatitis C, Infection, Pregnant females

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Section: Discussionmentioning

confidence: 99%

A Large Data Set; Hepatitis B and C Infection in Pregnant Females

Zafar¹,

Javed²,

Naveed³

et al. 2022

PJMHS

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“…This finding of older age predominance for HCV infection is similar to other studies in India and abroad. [21,22,23] Global elimination of HCV requires a multipronged approach as mandated by the WHO. Strategy and prevention of new infections is of equal importance to screening, diagnosing, and treating the existing HCV pool.…”

Section: Discussionmentioning

confidence: 99%

Sentinel Surveillance of HCV at Tertiary Care Hospital in Central India

Shrivastava

Jain²

2022

Int J Sci Healthcare Res

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Background: Hepatitis C virus (HCV) is a major cause of liver diseases like chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC). The prevalence of HCV infections is not uniform throughout India. Hence, the present study aimed to determine serological surveillance of HCV at tertiary care hospital in central India with a large population. Material and Methods: Between March 2019 and September 2022, the study was conducted on 8832 screening of HCV infection at a tertiary care hospital, Indore Madhya Pradesh. All these underwent diagnosis of HCV by serological ELISA method. Results: Total 126 cases were found positive for HCV infection. The seroprevalence was calculated as 1.4% (126/8832). The maximum (45.2%) positivity was observed in the sexually active group 19-39 years followed (33.3%) by the 40- 59 years age group. Although males were slightly more preponderant than females with HCV infection, statistically non-significant observed among them. Conclusion: The data of the current study will be helpful in taking prevention and control measures against HCV infection. Keywords: HCV, chronic hepatitis, prevalence

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Seroprevalence of hepatitis C virus among patients at a tertiary health care centre in Rajasthan, India

Cited by 2 publications

References 14 publications

A Large Data Set; Hepatitis B and C Infection in Pregnant Females

A Large Data Set; Hepatitis B and C Infection in Pregnant Females

Sentinel Surveillance of HCV at Tertiary Care Hospital in Central India

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