Seroprevalence of Helicobacter Pylori Infection among Patients with Gastroduodenal Disorders in Erbil City

Abstract

Background: More than half of the world's population is influenced by Helicobacter pylori infection. The infection is commonly obtained during childhood but may stay asymptomatic, with long-term clinical consequences such as gastritis, peptic ulcer illness, and stomach cancer. Objective: To determine the prevalence rate of Helicobacter pylori infection and related variables such as age, gender, residency, blood group, Rhesus factors and previous infection among patients presenting with gastroduodenal disorders in Erbil city. Patients and Methods: Out of 240 blood samples from patients with gastroduodenal disorders admitted to Rzgary Teaching Hospital in Erbil, Iraq from July to August 2019 were collected and screened for anti-Helicobacter pylori antibodies by rapid immunochromatographic assay, and blood groups of patients were determined by using hemagglutination test. For each study subject, a questionnaire sheet was prepared and used. Results: The overall prevalence rate of Helicobacter pylori infection among 240 patients with gastroduodenal disorders was 128 (53.3%). A significant relationship between Helicobacter pylori infection and gender (male 43.75% and female 59.72%) was recorded (P<0.05). The highest rate of Helicobacter pylori infection was founded among the age group over 50 years, but there were no significant differences between them (P>0.05). Prevalence was significantly higher among rural areas (60.4%) than the urban areas (48.6%) (P<0.05). There was a significant association between Helicobacter pylori infection and ABO blood group phenotypes (P<0.05), but there is no significant association between Helicobacter pylori infection and the type of Rhesus factor (P>0.05). Prevalence was significantly higher among the previous infection (78.5%) than non-previous infection (23.6%) (P<0.05). Conclusion: We found that in Erbil city, the seropositivity of anti-Helicobacter pylori antibody was high among patients with the gastroduodenal disorder. The high prevalence of Helicobacter pylori was founded in the women, elderly, rural area, O blood group, positive Rhesus factor and patients with the previous infection.

Association between Chronic Urticaria and Helicobacter pylori Infection among Patients Attending a Tertiary Hospital in Tanzania

“…Our findings were similar to Muhemmed and Khalis Mohammed, Alfahaad, Moesbehi et al, Majeed, and Jwan Saleh Khoshnaw [ 3 , 4 , 9 ] which explain that CU occurs mostly in adults. Our findings concur with the literature that CU is related to frequent, long duration, and prolonged exposure to allergens or causative agents for immunological reactions to occur [ 15 – 17 ]. These findings were different from the study done by Shin and Lee because their study population was children who aged less than 18 years [ 18 ].…”

“…pylori is as high as 90% because there is lack of proper sanitation, basic hygiene, poor diet, and overcrowding that favors H . pylori transmission, while in developed countries the prevalence is below 40% [ 8 , 10 , 15 , 17 ].…”

“…pylori infection with the risks that favors H . pylori transmission [ 3 , 4 , 17 , 20 ]. In addition, various H .…”

Seroprevelance of Helicobacter pylori Infection among Students of Bingham University, Karu in North-Central Nigeria

“…This work is similar to that carried out in China, (female 60% and male 45%); Taiwan (Female>59% and male 23%) and Egypt (Female 66% and males 32%). Similarly, [10] in Iraq reported a higher seroprevalence of 59.72% in females as against 43.75% in males. All these works showed the prevalence of the disease in women to be higher than that of men and was said to be as a result of the high social activities of women in the homes [27].…”

“…Conducting a study of seroprevalence of Helicobacter pylori infection among 240 patients with gastroduodenal disorders in Iraq, Majeed and Khoshnaw [10] reported 53.3% seropositivity, with a significant difference between male and female patients (43.75% and 59.72%, respectively). They considered their seropositivity high, and reported higher frequency of anti H. pylori antibodies among rural dwellers, females and patients with O blood group.…”