Seroprevalence of Dengue in Rural Tertiary Care Hospital at Puducherry-A Retrospective Study

Balamurugan, Ramadass; Shivekar, Sunil; Gopal, Robin; Kaviraj, M; Mangaiyarkarasi, T; Saleem, Muhammad

doi:10.20546/ijcmas.2016.506.016

Cited by 3 publications

(3 citation statements)

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“…More outdoor activities in adults may be one of the reasons for increased probability of exposure to infected mosquitoes. Our current study showed the highest rate of infection during the month of September and October which is the end of monsoon and beginning of post monsoon period in this region (8). It was also observed that number of positivity increases during monsoon season and immediate post monsoon season, when the environmental condition was favorable for breeding of the vector, i.e., Aedes aegypti.…”

Section: Discussionsupporting

confidence: 67%

“…In our previous study conducted in the year 2016 the prevalence rate was 13.9 %. 8 The prevalence rate (32.2%) has increased by two folds for the year 2017 in this study. Dengue incidence rate varies from time to time in a given location due to complex interactions among host, vector, virus and it is also proven that climatic factors also plays a role.…”

Section: Discussionsupporting

confidence: 45%

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Analysis of epidemiological and demographic component of dengue in rural Puducherry - A hospital based study

Mangaiyarkarasi¹,

Gopal²,

Shivekar³

et al. 2019

IJMR

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Introduction: Dengue Fever (DF) is caused by dengue virus (DENV) which is transmitted by the bite of Aedes aegypti mosquito. Incidence of DF is more rampant in tropical and subtropical areas with severe complications. This hospital based study is the analysis of surveillance data on the prevalence of dengue among the rural population of Puducherry, India. Materials and Methods: All patients admitted in our institution with the suspicion of dengue during the period of January 2017 to February 2018 were included in this study irrespective of age and sex. A total of 1880 patients were subjected for dengue screening by tests for NS1 antigen and IgM antibody by ELISA method and IgG antibody detection was done by rapid card test. Results: Out of 1880 included in this study, 32.2% (607) were diagnosed as positive for dengue. Among them 58.2% (353) were male. The mostly affected persons were from the category 21-30yrs (9.57%) followed by 31-40 yrs (6.48 %). A total of 48.3% (293) were found to be reactive for dengue NS1 antigen alone whereas 22.6% (137) and 2.9% (18) are reactive for IgM and IgG respectively. A peak in the number of incidence was observed during the month of October (N=256) followed by September (N=124) and minimum was observed during January and February (N=5). Conclusion: About 32.2% of the suspected cases were reactive for dengue by serology, which was a considerable increase in incidence when compared to the previous study in this region. The increased rate of incidence in male/active working age group shows that outdoor activities may be associated with high risk for the acquisition of dengue. Vector control measures and awareness campaigns explaining the inherent features of the disease and preventive measures shall be helpful in downsizing the incidence.

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Section: Discussionsupporting

confidence: 67%

Section: Discussionsupporting

confidence: 45%

Analysis of epidemiological and demographic component of dengue in rural Puducherry - A hospital based study

Mangaiyarkarasi¹,

Gopal²,

Shivekar³

et al. 2019

IJMR

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“…13 At the end of the acute phase of infection, serology is the main stay of diagnosis. [14][15][16][17] This study aims at detecting dengue antigen, antibodies and serotyping of viral RNA.…”

Section: Introductionmentioning

confidence: 99%

To estimate the prevailing Serotype of dengue virus and IgM antibody in suspected dengue fever cases

Sudha

Selvi²

2022

PJMS

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Dengue virus infection a vector borne disease affecting more than 50 million people worldwide annually. It is distributed in tropical and subtropical regions of the world, abundant in urban and semi-urban areas. It is the disease that spreads by bite of Aedes aegypti and Aedes albopictus mosquitoes. The virus being a RNA virus belongs to Flaviviridae family. The four serotypes of Dengue virus are DENV-1, DENV-2, DENV-3, and DENV-4 which have distinct antigenicity complex.This study was conducted in Microbiology Department, Government Stanley Medical College, Chennai, during the period Jan 2018 to Dec 2018 with 120 blood samples from patients of suspected dengue fever. Samples were selected by stratified random sampling method into three strata and each strata consisting of 40 samples based on duration of fever. All the samples were subjected to procedure for both NS1 antigen and IgM antibodies.15 NS1 positives samples with duration of fever less than 5 days were serotyped by PCR. : A total of 18 cases had NS1 antigen, 26 cases had IgM antibodies and 27 cases had both. A combination of the two tests detected a total of 44 cases. The chance of detection of NS1antigen decreased with duration of fever and IgM antibodies increased with duration of fever. The serotyping detected were DENV1 and DENV3 NS1 antigen detection by ELISA is useful in early phase of infection. A combination of NS1 ELISA and IgM ELISA have high sensitivity depending upon the duration of illness. Detection of DENV1 and DENV3 by PCR procedure helps to know the presence of prevailing serotype in this particular region which would be a good guide to predict the recurrence of outbreak and for efficient prevention and management.

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Assessment of breeding sites and seroprevalence of dengue in an urban area of Puducherry – A community-based study

et al. 2022

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Seroprevalence of Dengue in Rural Tertiary Care Hospital at Puducherry-A Retrospective Study

Cited by 3 publications

References 2 publications

Analysis of epidemiological and demographic component of dengue in rural Puducherry - A hospital based study

Analysis of epidemiological and demographic component of dengue in rural Puducherry - A hospital based study

To estimate the prevailing Serotype of dengue virus and IgM antibody in suspected dengue fever cases

Assessment of breeding sites and seroprevalence of dengue in an urban area of Puducherry – A community-based study

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