Seroprevalence of contagious caprine pleuropneumonia in Kefta Humera, Alamata (Tigray) and Aba-‘ala (Afar), Northern Ethiopia

Hadush, Birhanu; Eshetu, Lisanework; Mengistu, Wubishet; Hailesilassie, Mekonnen

doi:10.1007/s11250-008-9255-x

Cited by 24 publications

(26 citation statements)

References 4 publications

(3 reference statements)

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“…The overall seroprevalence of CCPP in the study areas was 31.6% (95% CI= 27.57-35.64%). The finding in the present study was in line with reports of Hadush et al (2009) 32.68% in Tigray and Afar, Sharew et al (2005) 29% in Wollo and Eshetu et al (2007) 31% in an export abattoir from goats that had been collected from Borana, Afar, Bale and Jinka. Similarly, Sherif et al (2012), Mohammed (2008) and Ingle et al (2008) had reported seroprevalence of 32.63% in selected districts of Jijiga Zone, 32% in Eastern Ethiopia and 33.67% in Nagpur District of Vidarbha region of India, respectively.…”

Section: Discussionsupporting

confidence: 93%

Seroprevalence of contagious caprine pleuropneumonia and field performance of inactivated vaccine in Borana pastoral area, southern Ethiopia

Lakew¹,

Sisay²,

Ayelet³

et al. 2014

Afr. J. Microbiol. Res.

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This study was conducted between September 2012 and May 2013 in three Districts of Borana pastoral area to determine seroprevalence of contagious caprine pleuropneumonia (CCPP) and assess field performance of inactivated commercial vaccine, produced by the National Veterinary Institute (NVI) in Ethiopia, against CCPP. Both pre and post vaccination sera samples were tested using competitive enzyme linked immunosorbent assay (cELISA). Out of 510 examined sera, 161 samples were positive for CCPP, giving an overall seroprevalence of 31.6% (95% CI = 27.57-35.64%) in the study area. Seroprevalence of 35.2, 35.1 and 25% were recorded in Arero, Dhas and Yabello districts, respectively. However, there was no significant difference (χ2=5.56, P=0.062) in seropositivity among the three districts and between male and female goats (χ2=0.068, P=0.794) examined in this study. On the other hand, the differences in seroprevalence among the age categories were statistically significant (χ2=24.48, p<0.0001). A rise in antibody (seroconversion) was observed after field vaccination of goats with inactivated CCPP vaccine and a total of 253 of the 414 examined sera samples were positive for Mycoplasma capricolum subsp. capripneumoniae (Mccp) specific antibodies, thus 61.1% of goats seroconverted following vaccination. Comparison of Mccp specific antibodies in the goat population before and after vaccination indicated that the number of positive reactors increased significantly (P<0.0001) following CCPP vaccination. Seropositivity following vaccination was analyzed among the three age groups and statistically significant differences (χ2=45.48, P<0.0001) were recorded. The change in the serum antibody after vaccination was found to be higher in younger and adult aged goats than old aged goats. In conclusion, the present study indicates that CCPP is one of the major goat health problems in Borana pastoral area which warrants appropriate measures to be in place towards the prevention and control of the disease. Moreover, field vaccination of goats by inactivated CCPP vaccine induced seropositivity in majority of the inoculated goats. Future controlled experimental studies with challenge infection after vaccination need to be conducted for further evaluation of the vaccine efficacy.

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Section: Discussionsupporting

confidence: 93%

Seroprevalence of contagious caprine pleuropneumonia and field performance of inactivated vaccine in Borana pastoral area, southern Ethiopia

Lakew¹,

Sisay²,

Ayelet³

et al. 2014

Afr. J. Microbiol. Res.

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“…The sero-prevalence of the disease was not significantly different between the two districts, Agago (17.7%) and Otuke (23.3%). This is not surprising since Agago and Otuke lie within the same agro ecological zone, a similar explanation earlier reported in Ethiopia [18].…”

Section: Discussionsupporting

confidence: 89%

“…This is close to what has been reported (15% -18%) in southern Ethiopia [4] [11]. Our finding was at variance with reports of studies done in Ethiopia [17] [18] and in Beetal goats in Pakistan Hussain, 2012 #51 as well as in East Turkey [19] who documented higher sero-prevalence between 31% and 38%. The sero-prevalence of the disease was not significantly different between the two districts, Agago (17.7%) and Otuke (23.3%).…”

Section: Discussionsupporting

confidence: 75%

“…Never the less, this findings were in disagreement with high efficacy reported with inactivated Mycoplasma strain F38 saponin vaccine in natural infection with CCPP [20]- [22] and experimentally lyophilized killed F38 vaccine that conferred 100% protection against mortality and 95% clinical disease of Mycoplasma species strains F38 [23]. Seroprevalence done in Tanzania [24] and in Ethiopia [4] [18] have also shown no sex difference in CCPP epidemiology.…”

Section: Discussionmentioning

confidence: 87%

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A Survey for Contagious Caprine Pleuropneumonia in Agago and Otuke Districts in Northern Uganda

Atim¹,

Ayebazibwe²,

Mwiine³

et al. 2016

OJVM

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Background: Contagious Caprine Pleuropneumonia (CCPP) is a devastating disease of goats caused by Mycoplasma capricolum subsp. Capripneumoniae (Mccp). The disease was first confirmed in Uganda in 1995 in Karamoja region. Contagious Caprine Pleuropneumonia negatively impacts on goats' productivity but its extent and magnitude among the local communities in Uganda remain unknown. A cross sectional study was conducted in the districts of Agago and Otuke neighboring Karamoja in Northern Uganda during the months of July and August 2011 to explore for the status of the disease. Methods: Five hundred and four serum samples from goats were obtained from randomly selected unvaccinated herds and 100 goats from vaccinated herds. Serum samples were examined for antibodies against Mycoplasma capricolum subsp. Capripneumoniae (Mccp) by ELISA method. A total of 162 semi-structured questionnaires were administered to selected farmers to obtain information on their understanding of the disease and the risk factors they associated with CCPP. Eight focus group discussions were also conducted with selected farmer groups to obtain detailed qualitative information on CCPP. Results: Among the unvaccinated goats, seroprevalence of CCPP was 32 (17.7%) and 52 (23.3%) for Agago and Otuke districts respectively. Levels of antibodies against Mccp were higher among vaccinated goats than unvaccinated ones (mean optical densities (ODs) of 0.905 and 0.776, p = 0.08). Majority of the farmers 121 (74.7%) had knowledge on CCPP and recognized that CCPP was among the major challenges to goat production in Uganda. Conclusions: This study demonstrated that CCPP was prevalent in Agago and Otuke districts, which are outside but close to Karamoja region where the disease was previously confirmed. There is a need for wider and detailed studies to investigate further CCPP in other districts of Uganda for effective preventive and control of CCPP in Uganda and the neighboring countries.

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“…CCPP is one of the major goat diseases in parts of Africa, the Middle East, and Asia (López 2007). Hadush et al (2009) reported a 32.68% seroprevalence in goats from northern Ethiopia. Transport, nutritional, and heat stresses during transit to slaughter houses could precipitate pneumonic pasteurellosis.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary adenomatosis and maedi-visna in Ethiopian central highland sheep: a microscopic study

Woldemeskel

Tibbo²

2009

Trop Anim Health Prod

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Microscopic examination of pneumonic lungs of the Ethiopian highland sheep (n = 35) was made and compared with the pneumonic lungs from ten sheep and 66 goats from the lowlands. Lesions compatible with sheep pulmonary adenomatosis (SPA; 8/35, 22.8%), and maedi-visna (MV; 9/35, 25.7%) were recorded only in sheep from the central highlands. Interstitial pneumonia (43.2%), bronchopneumonia (35.1%), and verminous pneumonia (6.3%) were recorded in both sheep and goats from the high- and the lowlands. SPA was documented for the first time in sheep from Ethiopia in this report. We believe that MV and SPA were introduced into Ethiopia through importation of exotic sheep. These infections should be considered in dealing with the diagnosis of respiratory diseases in all the sheep breeds in the central highlands and in the exotic and the crossbred sheep in the other parts of the country.

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Seroprevalence of contagious caprine pleuropneumonia in Kefta Humera, Alamata (Tigray) and Aba-‘ala (Afar), Northern Ethiopia

Cited by 24 publications

References 4 publications

Seroprevalence of contagious caprine pleuropneumonia and field performance of inactivated vaccine in Borana pastoral area, southern Ethiopia

Seroprevalence of contagious caprine pleuropneumonia and field performance of inactivated vaccine in Borana pastoral area, southern Ethiopia

A Survey for Contagious Caprine Pleuropneumonia in Agago and Otuke Districts in Northern Uganda

Pulmonary adenomatosis and maedi-visna in Ethiopian central highland sheep: a microscopic study

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