Seroprevalence of chikungunya in southern Odisha

Abstract

Background:The emergence of chikungunya (CHIK) infection was observed in Odisha, India in 2006. Thereafter many cases with symptoms suggestive of CHIK were reported from different districts of Southern-Odisha. This study was aimed to know the seroprevalence, clinical presentations and seasonal trends of CHIK infection in this region.Materials and Methods:This study was conducted in a tertiary hospital of this region. Serum samples received in the Department of Microbiology from various districts of Southern-Odisha from April 2011 to March 2012 were included in the study. The samples were tested for CHIK and dengue Immunoglobin M (IgM) antibodies by enzyme-linked immunosorbent assay and malaria parasite by immunochromatographic test (ICT) method.Results:Out of the 678 serum samples tested, 174 were positive for CHIK, 15 for dengue and two samples were positive for both CHIK and dengue IgM antibodies. The most affected age group was 16-45 years. Females were more affected than males.Conclusion:The seroprevalence of CHIK among the suspected cases was 25.7%. Co-infection with CHIK and dengue was found to be 1.15%. The infection had spread to new areas during this outbreak.

Prevalence of IgG and IgM antibodies to Chikungunya virus among outpatients with febrile illness attending University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria

“…It was observed in this study that the age group ≤60 years of age were found to be more susceptible to CHIKV infection which is in consonance with previous reports (Mohanty et al, 2013;Patil et al, 2013). This is the most active age group and coupled with movement of people outdoors during the day time when the activity of A. albopictus is at its peak, lesser personal protection and individual difference in immune response to diseases are some of the speculative reasons for increased susceptibility to CHIKV infection in this age group.…”

“…This could be attributed to the increased vector abundance and activity during rainy season as observed in study and in previous investigations (Mavalankar et al, 2008;Suryawanshi et al, 2009;Balasubramaniam et al, 2011;Dwibed et al, 2011;Mohanty et al, 2013). The patients in the present study that exhibited fever and headache were observed to show the highest prevalence of CHIKV antibody which could be the major symptoms of CHIKV infection in this environment.…”

“…The males are usually engaged in occupations that may expose them to bites by the vectors. However, the present finding disagrees with the earlier reports (Balasubramaniam et al, 2011;Dwibedi et al, 2011;Mohanty et al, 2013). The difference may probably be as a result of difference in geographical location and presence of socio-economic factors that facilitated the breeding of Aedes vector in their study area.…”

“…In addition, the absence of CHIK IgG only is an indication that the CHIKV infection is not endemic during the study period. However, these observations contrasted with other studies (Sergon et al, 2008;Gerardin et al, 2008;Kumar et al, 2010;Sissoko et al, 2008 andMohanty et al, 2013). The difference could be attributed to difference in geographical locations and periods of studies and could be attributed to the exposure of the population engaged in the rubber plantation to the infective biting of…”

Seroprevalence of Chikungunya among Febrile Patients in a Tertiary Care Hospital

“…The acute phase lasts for 2-3 days and may remit for 1-2 days after a gap of 4-10 days resulting in a "saddle back" fever curve (Mohanty et al, 2013). Most infections completely resolve within weeks but there are reported cases of CHIK V induced arthralgia lasting for months or even for years in the form of recurrent or persistent episodes (Narayan Shrihari et al, 2012).…”