Abstract:Progressive multifocal leukoencephalopathy (PML) is an infectious and opportunistic disease caused by the John Cunningham virus (JCV), in a immunusupresion state, JCV can be reactivated. In patients with recurrent remitting multiple sclerosis (RRMS), the immunosuppressants or immunoregulators are administered as disease-modifying treatment, one of them is natalizumab, unfortunately, it has been associated with the development of PML. The quantification of JCVAb is of particular interest since it has been direc… Show more
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