Seroprevalance of Transfusion Transmitted Infections(ttis) Among Blood Donors: A Retrospective Study From a Tertiary Care Hospital in North India.

Abstract

A transfusion transmitted infection (TTI) is any infection that is transmissible from person to- person through parenteral administration of blood or blood products.Blood transfusion carries the risk of transmitting infections like HIV,Hepatitis B,Hepatitis C,syphilis and malaria.So in order to provide safe blood transfusion these mandatory tests need to be done with proper monitoring.Aim To determine the seroprevalence of transfusion transmitted infections(TTIs) among blood donors. Materials and method The present study was conducted in department of hematology and transfusion medicine, Govt lal ded(LD) hospital Srinagar.Study period was from September 2020 to August 2021.A total number of 7235 donors were screened for HIV,HBV,HCV,Syphlis and malaria by ELISA and NAT test Results Out of 7235 donors, 99.23% were males,0.77% were females.0.98% were reactive for TTI.HBV 0.44%, HCV 0.46%,HIV 0.003% and syphilis 0.08% were the major infections in blood donors. None was positive for malaria. Conclusion Seropositivity of HBV,HIV,HCV,Syphilis and malaria among healthy donors indicates the risk of transfusion transmitted infections during blood transfusion.With the implementation of strict donor criteria and use of sensitive screening tests,it may be possible to reduce the incidence of TTI in the Indian scenario.