Seronegative Polyarthritis in Association With Anti-NXP2 Antibodies: A Case Series

Mourot, Aurélie; Bourré‐Tessier, Josiane; Nadon, Valérie; Landon‐Cardinal, Océane

doi:10.3899/jrheum.220248

J Rheumatol

2022

DOI: 10.3899/jrheum.220248

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Seronegative Polyarthritis in Association With Anti-NXP2 Antibodies: A Case Series

Aurélie Mourot

Josiane Bourré‐Tessier

Valérie Nadon

et al.

Abstract: Antinuclear matrix protein 2 (anti-NXP2) are dermatomyositis (DM)-specific autoantibodies.1 A recent metanalysis outlined their association with muscle weakness, myalgia, dysphagia, edema, and calcinosis.2

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2023

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Cited by 2 publications

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Update on autoantibodies and related biomarkers in autoimmune inflammatory myopathies

Choi,

Satoh,

Fritzler

2023

Current Opinion in Rheumatology

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Purpose of review This manuscript reviews recently published advances in the identification of autoimmune inflammatory myopathies (AIM)-specific and AIM-related autoantibodies considered of value in the workup of patients suspected of having AIM. Newer autoantibodies, developments, and advances in the methodology of testing, the gaps and pitfalls in using these assays as diagnostic biomarkers, and the importance of considering overlap diseases and unique clinical AIM phenotypes are discussed. Recent findings Summary The spectrum of autoantibodies and related biomarkers in AIM continues to expand. Many of these have clear clinical implications in regard to subsets and overlap conditions of AIM, associated malignancy and pathological findings.

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Update on autoantibodies and related biomarkers in autoimmune inflammatory myopathies

Choi,

Satoh,

Fritzler

2023

Current Opinion in Rheumatology

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Calcinosis in juvenile dermatomyositis: Updates on pathogenesis and treatment

Pinotti

Cannon²,

Dvergsten³

et al. 2023

Front. Med.

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Calcinosis, or the deposition of insoluble calcium salts in the skin, subcutaneous tissue, fascia, tendons, and muscles, is a feared complication of juvenile dermatomyositis. Calcinosis is estimated to affect up to 40% of patients with juvenile dermatomyositis and contributes to significant disease morbidity. Calcinosis can be challenging to treat, and the most effective treatment remains unknown because of a lack of comparative studies. We aim to review the literature published in the last 5 years to summarize updates on the pathogenesis and treatment of calcinosis in juvenile dermatomyositis and describe future areas for research.

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Seronegative Polyarthritis in Association With Anti-NXP2 Antibodies: A Case Series

Abstract: Antinuclear matrix protein 2 (anti-NXP2) are dermatomyositis (DM)-specific autoantibodies.1 A recent metanalysis outlined their association with muscle weakness, myalgia, dysphagia, edema, and calcinosis.2

Cited by 2 publications

References 9 publications

Update on autoantibodies and related biomarkers in autoimmune inflammatory myopathies

Update on autoantibodies and related biomarkers in autoimmune inflammatory myopathies

Calcinosis in juvenile dermatomyositis: Updates on pathogenesis and treatment

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