Serological tests for treponemal disease in adults in two Jamaican communities.

Ashcroft, Michael; Miall, W. E.; Standard, K. L.; Urquhart, A. E.

doi:10.1136/sti.43.2.96

Sexually Transmitted Infections

1967

DOI: 10.1136/sti.43.2.96

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Serological tests for treponemal disease in adults in two Jamaican communities.

Michael Ashcroft¹,

W. E. Miall²,

K. L. Standard³

et al.

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1978

1997

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Cited by 2 publications

References 10 publications

(8 reference statements)

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Modified neurosyphilis.

1978

BMJ

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The classical descriptions of tabes dorsalis, general paralysis of the insane (GPI), and meningovascular syphilis have been familiar to generations of medical students. Nevertheless, in their fully developed forms these diseases have become rarities in advanced countries. Though ankle reflexes) were the most frequent, though the least specific, but one-third of the patients had signs of posterior column lesions. In those attending for routine medical examination ophthalmic signs were the most common abnormality; these included pupillary changes, ptosis, uveitis, and choroidoretinitis. All the patients had positive blood FTA-ABS, but reagin tests were positive in only 117 (48.8%); similar serological results were obtained in those specimens of cerebrospinal fluid examined, all being reactive in the FTA-ABS but only about one-half showing reagin.Broadly comparable findings have been reported by Joyce-Clark and Molteno4 in a recent study of neurosyphilis in the Cape Peninsula, though many of their patients had been referred by ophthalmologists with suspicious ocular signs. They concluded that the most reliable and consistently helpful diagnostic features were abnormal pupillary reflexes, the blood FTA-ABS reaction, and raised concentrations of protein in the cerebrospinal fluid. Cerebrospinal fluid serology and the cell count were far less reliable markers. Included in the groups with "diagnostic" or "suspicious" signs were a subgroup of 13 patients with totally negative blood reactions, the diagnosis here depending on clinical signs and raised protein concentrations in the cerebrospinal fluid which declined after treatment.

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Modified neurosyphilis.

1978

BMJ

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Diagnosis of neurosyphilis: appraisal of clinical caseload.

Rodgers

Murphy

1997

Sexually Transmitted Infections

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Serological tests for treponemal disease in adults in two Jamaican communities.

Cited by 2 publications

References 10 publications

Modified neurosyphilis.

Modified neurosyphilis.

Diagnosis of neurosyphilis: appraisal of clinical caseload.

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